Institute of Cardiovascular Regeneration Webtool Repository

Transcript Accession	Transcript Name	Contained in Gene	Tax ID	Strand	Position	Biotype
Transcript Info
Description:	egl-9 family hypoxia-inducible factor 2
ENST00000303961	EGLN2-001	ENSG00000269858	9606	+	19:40799187-40808432	protein_coding

Transcript ID	Adipose	Adrenal	Bladder	Brain	Breast	Colon	Heart	Kidney	Liver	Lung	Muscle	Ovary	Placenta	Testis
ENST00000303961	23.715±0.00	39.061±0.00	1.704±0.00	11.826±4.89	35.539±0.00	16.524±14.23	10.845±9.77	17.160±16.33	11.211±7.02	40.085±37.52	11.817±0.00	50.828±8.51	42.569±17.25	54.651±0.00

Conserved Regions
Gene is not located within a conserved region.

Gene Ontology
GO ID	Evidence Type	GO Description
GO:0001558	NAS	regulation of cell growth
GO:0001666	IDA	response to hypoxia
GO:0005506	IEA	iron ion binding
GO:0005515	IPI	protein binding
GO:0005634	IDA	nucleus
GO:0005654	TAS	nucleoplasm
GO:0008198	NAS	ferrous iron binding
GO:0016491	IEA	oxidoreductase activity
GO:0016705	IEA	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0016706	IDA:IEA	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0018401	IDA	peptidyl-proline hydroxylation to 4-hydroxy-L-proline
GO:0019826	IDA	oxygen sensor activity
GO:0030520	NAS	intracellular estrogen receptor signaling pathway
GO:0031418	IEA	L-ascorbic acid binding
GO:0031545	IDA	peptidyl-proline 4-dioxygenase activity
GO:0043523	IMP	regulation of neuron apoptotic process
GO:0045454	IDA	cell redox homeostasis
GO:0045732	IDA	positive regulation of protein catabolic process
GO:0055114	IEA	oxidation-reduction process
GO:0061418	TAS	regulation of transcription from RNA polymerase II promoter in response to hypoxia
GO:0071456	TAS	cellular response to hypoxia

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