C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: egl-9 family hypoxia-inducible factor 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000080058 Egln2-001 ENSMUSG00000058709 10090 - 7:27158658-27166802 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000080058
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000080058 30.480±6.27 26.747±2.28 32.656±2.09 56.409±4.73 31.763±10.87 36.302±4.14 21.165±2.49 32.350±3.34 23.542±3.37 39.147±2.26 46.370±1.41 32.790±12.77 26.538±5.73 147.306±43.21

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007H6 CIL_0007H6_000M CGP 7:27119909-27158668

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001666 ISS response to hypoxia
GO:0005506 IEA iron ion binding
GO:0005515 IEA protein binding
GO:0005634 ISS nucleus
GO:0005829 IEA cytosol
GO:0016706 ISS oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0018401 IEA peptidyl-proline hydroxylation to 4-hydroxy-L-proline
GO:0019826 ISS oxygen sensor activity
GO:0031418 IEA L-ascorbic acid binding
GO:0031543 IEA peptidyl-proline dioxygenase activity
GO:0031545 IEA peptidyl-proline 4-dioxygenase activity
GO:0043523 ISS regulation of neuron apoptotic process
GO:0045454 ISS cell redox homeostasis
GO:0045732 ISS positive regulation of protein catabolic process
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000303961 EGLN2-001 protein_coding Homo_sapiens 0 1050
ENST00000406058 EGLN2-002 protein_coding Homo_sapiens 0 1050
ENST00000593397 EGLN2-011 protein_coding Homo_sapiens 0 455
ENST00000593445 EGLN2-017 retained_intron Homo_sapiens 0 630
ENST00000593477 EGLN2-005 retained_intron Homo_sapiens 0 424
ENST00000593525 EGLN2-018 protein_coding Homo_sapiens 0 457
ENST00000593726 EGLN2-003 protein_coding Homo_sapiens 0 1050
ENST00000593972 EGLN2-007 protein_coding Homo_sapiens 0 699
ENST00000594136 RAB4B-EGLN2-003 nonsense_mediated_decay Homo_sapiens 0 1050
ENST00000594140 EGLN2-015 protein_coding Homo_sapiens 0 627
ENST00000594380 EGLN2-010 protein_coding Homo_sapiens 0 499
ENST00000595051 EGLN2-014 protein_coding Homo_sapiens 0 248
ENST00000595621 EGLN2-013 protein_coding Homo_sapiens 0 327
ENST00000596517 EGLN2-008 protein_coding Homo_sapiens 0 448
ENST00000597746 EGLN2-012 protein_coding Homo_sapiens 0 425
ENST00000598654 EGLN2-006 protein_coding Homo_sapiens 0 540
ENST00000599579 EGLN2-004 retained_intron Homo_sapiens 0 436
ENST00000601733 EGLN2-009 protein_coding Homo_sapiens 0 518
ENST00000602166 EGLN2-016 retained_intron Homo_sapiens 0 436

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