C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: O-6-methylguanine-DNA methyltransferase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000306010 MGMT-001 ENSG00000170430 9606 + 10:129467184-129768007 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000306010
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000306010 6.659±0.00 8.138±0.00 3.417±0.00 3.483±0.58 7.261±4.48 4.992±2.13 2.406±0.99 12.080±4.81 13.063±8.51 5.481±3.25 3.465±0.84 7.045±4.45 8.314±4.19 10.341±4.46

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001LH CIL_0001LH_0001 CGP 10:128096659-129768007
CIL_0007OP CIL_0007OP_0001 UCNEbase 10:128166009-130159815
CIL_0007TK CIL_0007TK_0001 VISTA 10:129008258-129610478
CIL_00081R CIL_00081R_0001 VISTA 10:129302684-129904015
CIL_00097C CIL_00097C_0001 VISTA 10:129305804-129907046
CIL_0009BD CIL_0009BD_0001 VISTA 10:129347523-129949421
CIL_0008TP CIL_0008TP_0001 VISTA 10:129416557-130017922
CIL_0001LI CIL_0001LI_0001 CGP 10:129467184-129963841

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003677 IEA DNA binding
GO:0003824 IEA catalytic activity
GO:0003908 IEA methylated-DNA-[protein]-cysteine S-methyltransferase activity
GO:0005509 IEA calcium ion binding
GO:0005634 TAS nucleus
GO:0005654 TAS nucleoplasm
GO:0006266 TAS DNA ligation
GO:0006281 TAS:IEA DNA repair
GO:0006306 TAS DNA methylation
GO:0006307 IEA DNA dealkylation involved in DNA repair
GO:0006974 IEA cellular response to DNA damage stimulus
GO:0008168 TAS methyltransferase activity
GO:0009008 TAS DNA-methyltransferase activity
GO:0009636 IEA response to toxic substance
GO:0014070 IEA response to organic cyclic compound
GO:0016020 IDA membrane
GO:0034599 IEA cellular response to oxidative stress
GO:0042493 IEA response to drug
GO:0043281 IEA regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0045471 IEA response to ethanol
GO:0045739 IEA positive regulation of DNA repair
GO:0051593 IEA response to folic acid
GO:0060548 IEA negative regulation of cell death
GO:0060644 IEA mammary gland epithelial cell differentiation
GO:0071407 IEA cellular response to organic cyclic compound
GO:0071479 IEA cellular response to ionizing radiation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000081510 Mgmt-201 protein_coding Mus_musculus 0 357

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