C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: v-rel avian reticuloendotheliosis viral oncogene homolog A
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000308639 RELA-002 ENSG00000173039 9606 - 11:65653602-65663090 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainColonKidneyLiverTestisENST00000308639
Transcript ID Adipose Brain Colon Kidney Liver Testis
ENST00000308639 9.453±0.00 3.443±2.92 4.574±3.59 5.847±0.00 1.326±0.00 8.004±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008W1 CIL_0008W1_0001 VISTA 11:65187233-65790923

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000980 IDA RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001078 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0001205 IDA RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0002224 TAS toll-like receptor signaling pathway
GO:0002755 TAS MyD88-dependent toll-like receptor signaling pathway
GO:0002756 TAS MyD88-independent toll-like receptor signaling pathway
GO:0003677 IDA DNA binding
GO:0003682 IDA chromatin binding
GO:0003700 IDA:IEA sequence-specific DNA binding transcription factor activity
GO:0003705 IDA RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA:IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0005667 IDA transcription factor complex
GO:0005737 IDA cytoplasm
GO:0005829 IDA cytosol
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006954 IDA inflammatory response
GO:0006968 NAS cellular defense response
GO:0008134 IPI transcription factor binding
GO:0008284 IDA positive regulation of cell proliferation
GO:0010033 IDA response to organic substance
GO:0010224 IDA response to UV-B
GO:0016032 IEA viral process
GO:0019221 IDA cytokine-mediated signaling pathway
GO:0019901 IPI protein kinase binding
GO:0031293 TAS membrane protein intracellular domain proteolysis
GO:0031625 IPI ubiquitin protein ligase binding
GO:0032481 TAS positive regulation of type I interferon production
GO:0033613 IPI activating transcription factor binding
GO:0034134 TAS toll-like receptor 2 signaling pathway
GO:0034138 TAS toll-like receptor 3 signaling pathway
GO:0034142 TAS toll-like receptor 4 signaling pathway
GO:0034146 TAS toll-like receptor 5 signaling pathway
GO:0034162 TAS toll-like receptor 9 signaling pathway
GO:0034166 TAS toll-like receptor 10 signaling pathway
GO:0035666 TAS TRIF-dependent toll-like receptor signaling pathway
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0038123 TAS toll-like receptor TLR1:TLR2 signaling pathway
GO:0038124 TAS toll-like receptor TLR6:TLR2 signaling pathway
GO:0042301 IDA phosphate ion binding
GO:0042802 IPI identical protein binding
GO:0043066 IDA negative regulation of apoptotic process
GO:0043123 IEP positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0044212 IDA transcription regulatory region DNA binding
GO:0045087 TAS innate immune response
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0047485 IPI protein N-terminus binding
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0050727 ISS regulation of inflammatory response
GO:0050852 TAS T cell receptor signaling pathway
GO:0051059 IPI NF-kappaB binding
GO:0051092 IDA positive regulation of NF-kappaB transcription factor activity
GO:0051607 NAS defense response to virus
GO:0070301 IDA cellular response to hydrogen peroxide
GO:0070431 IDA nucleotide-binding oligomerization domain containing 2 signaling pathway
GO:0070491 IPI repressing transcription factor binding
GO:0070555 IGI response to interleukin-1
GO:0071316 IMP cellular response to nicotine
GO:0071347 IDA cellular response to interleukin-1
GO:0071354 IMP cellular response to interleukin-6
GO:0071356 IDA cellular response to tumor necrosis factor
GO:0071375 IMP cellular response to peptide hormone stimulus
GO:2000630 IMP positive regulation of miRNA metabolic process
GO:2001237 IMP negative regulation of extrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000025867 Rela-001 protein_coding Mus_musculus 0 2028

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