C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: v-rel reticuloendotheliosis viral oncogene homolog A (avian)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000025867 Rela-001 ENSMUSG00000024927 10090 + 19:5637483-5648130 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000025867
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000025867 32.263±2.04 63.455±4.63 26.092±0.07 11.305±3.42 29.165±9.65 22.313±3.85 11.312±1.79 17.148±2.03 15.072±3.63 43.165±1.84 6.389±0.50 34.369±6.87 14.961±9.60 11.525±3.84

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008W1 CIL_0008W1_0002 VISTA 19:5510095-6112698

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0000978 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000980 IEA RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0001077 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001078 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0001205 IEA RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001889 IMP liver development
GO:0001942 IMP hair follicle development
GO:0003677 IDA DNA binding
GO:0003682 IDA chromatin binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0003705 IDA RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005667 IEA transcription factor complex
GO:0005737 IDA cytoplasm
GO:0005829 IDA cytosol
GO:0006117 IEA acetaldehyde metabolic process
GO:0006366 IDA transcription from RNA polymerase II promoter
GO:0006952 IMP defense response
GO:0006954 IEA inflammatory response
GO:0007568 IEA aging
GO:0008134 IEA transcription factor binding
GO:0008284 ISS positive regulation of cell proliferation
GO:0009612 IEA response to mechanical stimulus
GO:0009617 IDA response to bacterium
GO:0009887 IMP organ morphogenesis
GO:0010033 IEA response to organic substance
GO:0010035 IEA response to inorganic substance
GO:0010224 IEA response to UV-B
GO:0014040 IEA positive regulation of Schwann cell differentiation
GO:0014070 IEA response to organic cyclic compound
GO:0019221 IEA cytokine-mediated signaling pathway
GO:0019899 IPI enzyme binding
GO:0019901 IPI protein kinase binding
GO:0031625 IEA ubiquitin protein ligase binding
GO:0032332 IEA positive regulation of chondrocyte differentiation
GO:0032403 IEA protein complex binding
GO:0032495 IDA response to muramyl dipeptide
GO:0032496 IEA response to lipopolysaccharide
GO:0032570 IEA response to progesterone
GO:0032868 IEA response to insulin
GO:0033590 IEA response to cobalamin
GO:0033613 IEA activating transcription factor binding
GO:0034097 IEA response to cytokine
GO:0042177 IMP negative regulation of protein catabolic process
GO:0042301 IEA phosphate ion binding
GO:0042493 IEA response to drug
GO:0042542 IEA response to hydrogen peroxide
GO:0042802 IEA identical protein binding
GO:0043066 IDA negative regulation of apoptotic process
GO:0043123 IDA positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043200 IEA response to amino acid
GO:0043234 IEA protein complex
GO:0043278 IEA response to morphine
GO:0043565 IDA sequence-specific DNA binding
GO:0044212 IEA transcription regulatory region DNA binding
GO:0045084 IDA positive regulation of interleukin-12 biosynthetic process
GO:0045892 IEA negative regulation of transcription, DNA-templated
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 ISS positive regulation of transcription from RNA polymerase II promoter
GO:0046627 IEA negative regulation of insulin receptor signaling pathway
GO:0047485 IEA protein N-terminus binding
GO:0050727 IDA regulation of inflammatory response
GO:0051059 IEA NF-kappaB binding
GO:0051092 ISO positive regulation of NF-kappaB transcription factor activity
GO:0051591 IEA response to cAMP
GO:0070301 ISS cellular response to hydrogen peroxide
GO:0070431 IEA nucleotide-binding oligomerization domain containing 2 signaling pathway
GO:0070491 IEA repressing transcription factor binding
GO:0070555 IEA response to interleukin-1
GO:0071159 TAS NF-kappaB complex
GO:0071222 IEP cellular response to lipopolysaccharide
GO:0071316 IEA cellular response to nicotine
GO:0071347 IEA cellular response to interleukin-1
GO:0071354 IEA cellular response to interleukin-6
GO:0071356 ISS cellular response to tumor necrosis factor
GO:0071375 IEA cellular response to peptide hormone stimulus
GO:0071532 IPI ankyrin repeat binding
GO:2000630 IEA positive regulation of miRNA metabolic process
GO:2001237 IDA negative regulation of extrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000308639 RELA-002 protein_coding Homo_sapiens 0 2028
ENST00000406246 RELA-001 protein_coding Homo_sapiens 0 2076
ENST00000414855 RP5-1166A24.1-001 processed_pseudogene Homo_sapiens 0 335
ENST00000525301 RELA-012 retained_intron Homo_sapiens 0 470
ENST00000525658 RELA-017 nonsense_mediated_decay Homo_sapiens 0 898
ENST00000525693 RELA-006 protein_coding Homo_sapiens 0 1365
ENST00000525858 RELA-010 retained_intron Homo_sapiens 0 588
ENST00000526283 RELA-008 nonsense_mediated_decay Homo_sapiens 0 894
ENST00000526738 RELA-019 retained_intron Homo_sapiens 0 424
ENST00000527074 RELA-026 retained_intron Homo_sapiens 0 616
ENST00000527749 RELA-014 protein_coding Homo_sapiens 0 791
ENST00000527874 RELA-016 protein_coding Homo_sapiens 0 436
ENST00000527909 RELA-023 nonsense_mediated_decay Homo_sapiens 0 424
ENST00000529330 RELA-020 retained_intron Homo_sapiens 0 237
ENST00000529389 RELA-025 nonsense_mediated_decay Homo_sapiens 0 712
ENST00000531238 RELA-021 nonsense_mediated_decay Homo_sapiens 0 564
ENST00000531484 RELA-005 retained_intron Homo_sapiens 0 1663
ENST00000532776 RELA-011 retained_intron Homo_sapiens 0 357
ENST00000532879 RELA-027 protein_coding Homo_sapiens 0 610
ENST00000532999 RELA-004 protein_coding Homo_sapiens 0 1166
ENST00000533187 RELA-013 protein_coding Homo_sapiens 0 464
ENST00000533546 RELA-024 nonsense_mediated_decay Homo_sapiens 0 427
ENST00000534305 RELA-018 retained_intron Homo_sapiens 0 379
ENST00000534558 RELA-022 protein_coding Homo_sapiens 0 773
ENST00000612991 RELA-201 protein_coding Homo_sapiens 0 1568
ENST00000615805 RELA-202 protein_coding Homo_sapiens 0 1022

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