C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: proprotein convertase subtilisin/kexin type 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000311106 PCSK1-001 ENSG00000175426 9606 - 5:96390415-96433280 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyMuscleOvaryPlacentaTestisENST00000311106
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Muscle Ovary Placenta Testis
ENST00000311106 0.473±0.00 0.123±0.00 2.260±0.76 5.361±0.00 0.222±0.08 0.062±0.00 0.026±0.00 0.095±0.00 0.100±0.11 0.019±0.01 0.056±0.03

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004175 IEA endopeptidase activity
GO:0004252 ISS:IEA serine-type endopeptidase activity
GO:0005615 IDA extracellular space
GO:0005794 IBA Golgi apparatus
GO:0006508 IEA proteolysis
GO:0007267 TAS cell-cell signaling
GO:0008152 TAS metabolic process
GO:0016485 IEA protein processing
GO:0016486 TAS peptide hormone processing
GO:0034774 TAS secretory granule lumen
GO:0043043 ISS peptide biosynthetic process
GO:0044267 TAS cellular protein metabolic process
GO:0050796 TAS regulation of insulin secretion

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000022075 Pcsk1-001 protein_coding Mus_musculus 0 2911
ENSMUST00000135349 Pcsk1-002 retained_intron Mus_musculus 0 939

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