C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: proprotein convertase subtilisin/kexin type 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000022075 Pcsk1-001 ENSMUSG00000021587 10090 + 13:75089826-75132498 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000022075
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000022075 0.075±0.05 3.912±0.33 0.042±0.00 4.024±3.70 0.059±0.04 3.497±0.40 0.031±0.01 0.015±0.00 0.003±0.00 0.237±0.14 0.050±0.03 0.090±0.03 0.014±0.01 0.094±0.04

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000JE CIL_0000JE_0002 CGP 13:74694286-75132498
CIL_00002O CIL_00002O_0002 CGP 13:75089826-75772356

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004175 IDA endopeptidase activity
GO:0004252 IDA serine-type endopeptidase activity
GO:0005615 IDA extracellular space
GO:0005788 TAS endoplasmic reticulum lumen
GO:0005794 IBA Golgi apparatus
GO:0006508 IEA proteolysis
GO:0016485 IDA protein processing
GO:0016486 IDA peptide hormone processing
GO:0034774 TAS secretory granule lumen
GO:0043043 IDA peptide biosynthetic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000131060 pcsk5a-201 protein_coding Danio_rerio 0.00000000004 75
ENSDART00000085314 pcsk5a-001 protein_coding Danio_rerio 0.00000000004 75
ENST00000311106 PCSK1-001 protein_coding Homo_sapiens 0 2911
ENST00000508626 PCSK1-002 protein_coding Homo_sapiens 0 2577
ENST00000513085 PCSK1-004 processed_transcript Homo_sapiens 0 1375

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