C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: peroxisome proliferator-activated receptor delta
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000311565 PPARD-002 ENSG00000112033 9606 + 6:35342614-35428178 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainOvaryENST00000311565
Transcript ID Brain Ovary
ENST00000311565 2.203±0.00 0.231±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008UQ CIL_0008UQ_0001 VISTA 6:35189352-35792826
CIL_0004LU CIL_0004LU_0002 CGP 6:35297852-35428191
CIL_0002EQ CIL_0002EQ_0001 CGP 6:35342558-35467103

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 ISS negative regulation of transcription from RNA polymerase II promoter
GO:0001890 IEA placenta development
GO:0003677 ISS DNA binding
GO:0003700 NAS:IEA sequence-specific DNA binding transcription factor activity
GO:0003707 IEA steroid hormone receptor activity
GO:0003713 IEA transcription coactivator activity
GO:0004879 IDA ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0005504 IEA fatty acid binding
GO:0005515 IPI protein binding
GO:0005634 NAS:IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0006006 NAS glucose metabolic process
GO:0006029 IEA proteoglycan metabolic process
GO:0006091 TAS generation of precursor metabolites and energy
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006357 TAS regulation of transcription from RNA polymerase II promoter
GO:0006367 TAS transcription initiation from RNA polymerase II promoter
GO:0006629 ISS lipid metabolic process
GO:0006635 ISS fatty acid beta-oxidation
GO:0006776 IEA vitamin A metabolic process
GO:0007507 IEA heart development
GO:0007566 TAS embryo implantation
GO:0008144 IDA drug binding
GO:0008203 TAS cholesterol metabolic process
GO:0008270 IEA zinc ion binding
GO:0008283 ISS cell proliferation
GO:0008284 IEA positive regulation of cell proliferation
GO:0008289 IDA lipid binding
GO:0008366 ISS axon ensheathment
GO:0008654 IEA phospholipid biosynthetic process
GO:0009062 TAS fatty acid catabolic process
GO:0009299 IEA mRNA transcription
GO:0009749 IEA response to glucose
GO:0010033 IEA response to organic substance
GO:0010467 TAS gene expression
GO:0014068 IEA positive regulation of phosphatidylinositol 3-kinase signaling
GO:0014823 IEA response to activity
GO:0014912 IEA negative regulation of smooth muscle cell migration
GO:0015758 NAS glucose transport
GO:0015908 ISS fatty acid transport
GO:0019395 IEA fatty acid oxidation
GO:0030154 IEA cell differentiation
GO:0030308 IEA negative regulation of cell growth
GO:0030522 IEA intracellular receptor signaling pathway
GO:0031589 IEA cell-substrate adhesion
GO:0032024 IEA positive regulation of insulin secretion
GO:0032966 IEA negative regulation of collagen biosynthetic process
GO:0033189 IEA response to vitamin A
GO:0042060 IEA wound healing
GO:0042127 IEA regulation of cell proliferation
GO:0043066 IEA negative regulation of apoptotic process
GO:0043401 IEA steroid hormone mediated signaling pathway
GO:0043565 IEA sequence-specific DNA binding
GO:0043616 IEA keratinocyte proliferation
GO:0045598 IEA regulation of fat cell differentiation
GO:0045600 NAS positive regulation of fat cell differentiation
GO:0045684 IEA positive regulation of epidermis development
GO:0045892 ISS negative regulation of transcription, DNA-templated
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045909 IEA positive regulation of vasodilation
GO:0046697 TAS decidualization
GO:0048662 IEA negative regulation of smooth muscle cell proliferation
GO:0050680 IEA negative regulation of epithelial cell proliferation
GO:0050728 IEA negative regulation of inflammatory response
GO:0051059 IEA NF-kappaB binding
GO:0051546 IEA keratinocyte migration
GO:0060612 IEA adipose tissue development
GO:0070539 IDA linoleic acid binding
GO:0071456 IEA cellular response to hypoxia
GO:0097190 IMP apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000002320 Ppard-001 protein_coding Mus_musculus 0 1729
ENSMUST00000166744 Ppard-004 processed_transcript Mus_musculus 0 1543
ENSMUST00000169040 Ppard-005 protein_coding Mus_musculus 0 1000
ENSMUST00000142226 Ppard-003 retained_intron Mus_musculus 0 911
ENSDART00000128783 ppardb-201 protein_coding Danio_rerio 0 518
ENSDART00000132584 ppardb-001 protein_coding Danio_rerio 0 518

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