C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: multiple endocrine neoplasia I
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000315422 MEN1-003 ENSG00000133895 9606 - 11:64803516-64810741 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonLungOvaryPlacentaTestisENST00000315422
Transcript ID Adipose Adrenal Brain Breast Colon Lung Ovary Placenta Testis
ENST00000315422 1.134±0.00 2.113±0.00 0.940±0.44 2.243±1.03 1.177±0.00 0.789±0.41 5.463±4.25 2.299±0.76 2.417±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005JE CIL_0005JE_0002 CGP 11:64788818-64811294

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000165 IDA MAPK cascade
GO:0000400 IDA four-way junction DNA binding
GO:0000403 IDA Y-form DNA binding
GO:0000785 IDA chromatin
GO:0001933 IDA negative regulation of protein phosphorylation
GO:0002076 IGI osteoblast development
GO:0003690 IDA double-stranded DNA binding
GO:0005515 IPI protein binding
GO:0005634 IEA:IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0005829 IDA cytosol
GO:0006281 NAS DNA repair
GO:0006351 TAS transcription, DNA-templated
GO:0006367 TAS transcription initiation from RNA polymerase II promoter
GO:0006974 IDA cellular response to DNA damage stimulus
GO:0007179 TAS transforming growth factor beta receptor signaling pathway
GO:0008285 IDA negative regulation of cell proliferation
GO:0009411 IDA response to UV
GO:0010332 IDA response to gamma radiation
GO:0010467 TAS gene expression
GO:0016363 IDA nuclear matrix
GO:0018024 IDA histone-lysine N-methyltransferase activity
GO:0030511 IMP positive regulation of transforming growth factor beta receptor signaling pathway
GO:0030674 IDA protein binding, bridging
GO:0032092 IDA positive regulation of protein binding
GO:0032154 IDA cleavage furrow
GO:0034968 IDA histone lysine methylation
GO:0035097 IPI histone methyltransferase complex
GO:0043234 IDA protein complex
GO:0043433 IDA negative regulation of sequence-specific DNA binding transcription factor activity
GO:0044212 IDA transcription regulatory region DNA binding
GO:0045668 IGI negative regulation of osteoblast differentiation
GO:0045736 IMP negative regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0045786 IDA negative regulation of cell cycle
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045944 TAS positive regulation of transcription from RNA polymerase II promoter
GO:0046329 IDA negative regulation of JNK cascade
GO:0047485 IPI protein N-terminus binding
GO:0051974 IMP negative regulation of telomerase activity
GO:0070412 IPI R-SMAD binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000113500 Men1-007 protein_coding Mus_musculus 0 2392
ENSMUST00000056391 Men1-003 protein_coding Mus_musculus 0 2289
ENSMUST00000113502 Men1-201 protein_coding Mus_musculus 0 2287
ENSMUST00000079327 Men1-002 protein_coding Mus_musculus 0 2287
ENSMUST00000113504 Men1-001 protein_coding Mus_musculus 0 2287
ENSMUST00000113503 Men1-008 protein_coding Mus_musculus 0 2183
ENSMUST00000078137 Men1-004 protein_coding Mus_musculus 0 1616
ENSMUST00000156154 Men1-006 retained_intron Mus_musculus 0 1450
ENSMUST00000113501 Men1-005 protein_coding Mus_musculus 0 1360
ENSMUST00000170132 Men1-011 protein_coding Mus_musculus 0 534
ENSMUST00000170292 Men1-010 nonsense_mediated_decay Mus_musculus 0 335
ENSMUST00000166909 Men1-009 protein_coding Mus_musculus 0 291

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