C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: multiple endocrine neoplasia 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000056391 Men1-003 ENSMUSG00000024947 10090 + 19:6335039-6340889 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000056391
Transcript ID Adipose Adrenal Bladder Brain Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000056391 2.650±0.76 3.177±0.25 2.114±0.52 8.097±1.57 2.397±0.26 0.849±0.00 2.425±0.23 2.168±0.98 2.478±0.00 0.924±0.62 4.476±0.43 5.886±1.58 1.496±0.01

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001YX CIL_0001YX_0002 CGP 19:6334979-6355615

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0001503 IMP ossification
GO:0001776 IMP leukocyte homeostasis
GO:0002051 IGI osteoblast fate commitment
GO:0002076 IGI osteoblast development
GO:0003677 IDA DNA binding
GO:0003682 IDA chromatin binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006338 IMP chromatin remodeling
GO:0006351 IEA transcription, DNA-templated
GO:0007050 IMP cell cycle arrest
GO:0008285 IMP negative regulation of cell proliferation
GO:0016571 IDA histone methylation
GO:0030097 IMP hemopoiesis
GO:0031062 IMP positive regulation of histone methylation
GO:0035097 ISO histone methyltransferase complex
GO:0043065 IDA positive regulation of apoptotic process
GO:0043280 IDA positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043565 IDA sequence-specific DNA binding
GO:0045597 IMP positive regulation of cell differentiation
GO:0045668 IDA negative regulation of osteoblast differentiation
GO:0045669 IGI positive regulation of osteoblast differentiation
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IGI positive regulation of transcription from RNA polymerase II promoter
GO:0046621 IDA negative regulation of organ growth
GO:0048704 IMP embryonic skeletal system morphogenesis
GO:0051781 IMP positive regulation of cell division
GO:0060021 IMP palate development
GO:0060135 IDA maternal process involved in female pregnancy

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000312049 MEN1-001 protein_coding Homo_sapiens 0 2289
ENST00000315422 MEN1-003 protein_coding Homo_sapiens 0 2289
ENST00000337652 MEN1-201 protein_coding Homo_sapiens 0 2218
ENST00000377313 MEN1-011 protein_coding Homo_sapiens 0 2213
ENST00000377316 MEN1-008 protein_coding Homo_sapiens 0 1650
ENST00000377321 MEN1-002 protein_coding Homo_sapiens 0 1360
ENST00000377326 MEN1-007 protein_coding Homo_sapiens 0 2425
ENST00000394374 MEN1-202 protein_coding Homo_sapiens 0 2218
ENST00000394376 MEN1-203 protein_coding Homo_sapiens 0 2218
ENST00000413626 MEN1-010 protein_coding Homo_sapiens 0 1083
ENST00000424912 MEN1-006 protein_coding Homo_sapiens 0 638
ENST00000429702 MEN1-005 protein_coding Homo_sapiens 0 638
ENST00000440873 MEN1-009 protein_coding Homo_sapiens 0 1445
ENST00000450708 MEN1-004 protein_coding Homo_sapiens 0 1166
ENST00000478548 MEN1-012 retained_intron Homo_sapiens 0 778

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