C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: mitogen-activated protein kinase 14
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000004990 Mapk14-001 ENSMUSG00000053436 10090 + 17:28691342-28748404 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonKidneyLiverLungOvaryPlacentaTestisENSMUST00000004990
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Kidney Liver Lung Ovary Placenta Testis
ENSMUST00000004990 6.901±0.69 5.973±0.46 5.404±0.00 14.242±0.98 9.930±2.54 7.781±0.67 7.445±1.46 6.198±2.79 7.079±0.04 9.676±3.17 7.565±1.62 1.503±0.47

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002O8 CIL_0002O8_0002 CGP 17:28637783-28748404
CIL_0002O5 CIL_0002O5_0002 CGP 17:28691342-28778698

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000077 IMP DNA damage checkpoint
GO:0000165 IEA MAPK cascade
GO:0000902 IGI cell morphogenesis
GO:0000922 IDA spindle pole
GO:0001502 IMP cartilage condensation
GO:0001525 IMP angiogenesis
GO:0002062 IDA:IMP chondrocyte differentiation
GO:0004672 IDA protein kinase activity
GO:0004674 IDA protein serine/threonine kinase activity
GO:0004707 IDA:ISS MAP kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005623 IDA cell
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005829 IDA cytosol
GO:0006006 IMP glucose metabolic process
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0006357 IMP regulation of transcription from RNA polymerase II promoter
GO:0006468 IDA protein phosphorylation
GO:0006915 IEA apoptotic process
GO:0006974 IDA cellular response to DNA damage stimulus
GO:0007178 IGI transmembrane receptor protein serine/threonine kinase signaling pathway
GO:0007519 IMP skeletal muscle tissue development
GO:0010831 IMP positive regulation of myotube differentiation
GO:0014835 IMP myoblast differentiation involved in skeletal muscle regeneration
GO:0016301 IDA kinase activity
GO:0018105 IDA peptidyl-serine phosphorylation
GO:0019395 IMP fatty acid oxidation
GO:0030316 IMP osteoclast differentiation
GO:0031663 IDA lipopolysaccharide-mediated signaling pathway
GO:0032495 IDA response to muramyl dipeptide
GO:0032496 IDA response to lipopolysaccharide
GO:0035556 ISS intracellular signal transduction
GO:0035924 IEA cellular response to vascular endothelial growth factor stimulus
GO:0038066 IDA p38MAPK cascade
GO:0042307 IMP positive regulation of protein import into nucleus
GO:0042770 IEA signal transduction in response to DNA damage
GO:0045648 IMP positive regulation of erythrocyte differentiation
GO:0045663 IMP positive regulation of myoblast differentiation
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0048010 IEA vascular endothelial growth factor receptor signaling pathway
GO:0051146 IGI striated muscle cell differentiation
GO:0051525 IPI NFAT protein binding
GO:0070062 IEA extracellular vesicular exosome
GO:0071222 ISO cellular response to lipopolysaccharide
GO:0071479 IEA cellular response to ionizing radiation
GO:0090090 IMP negative regulation of canonical Wnt signaling pathway
GO:0090336 IMP positive regulation of brown fat cell differentiation
GO:0090400 IEA stress-induced premature senescence
GO:1901741 IMP positive regulation of myoblast fusion
GO:2000379 IEA positive regulation of reactive oxygen species metabolic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000229794 MAPK14-002 protein_coding Homo_sapiens 0 1432
ENST00000229795 MAPK14-001 protein_coding Homo_sapiens 0 1626
ENST00000310795 MAPK14-004 protein_coding Homo_sapiens 0 837
ENST00000330651 MAPK11-001 protein_coding Homo_sapiens 0 405
ENST00000395764 MAPK11-003 nonsense_mediated_decay Homo_sapiens 0 405
ENST00000417877 MAPK11-002 nonsense_mediated_decay Homo_sapiens 0 387
ENST00000468133 MAPK14-003 protein_coding Homo_sapiens 0 1327
ENST00000474429 MAPK14-008 nonsense_mediated_decay Homo_sapiens 0 483
ENST00000491957 MAPK14-006 nonsense_mediated_decay Homo_sapiens 0 588
ENST00000496250 MAPK14-005 retained_intron Homo_sapiens 0 837
ENST00000622903 MAPK14-201 protein_coding Homo_sapiens 0 641

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