C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: suppressor of cytokine signaling 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000330871 SOCS3-001 ENSG00000184557 9606 - 17:78356778-78360077 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000330871
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000330871 41.031±0.00 73.118±0.00 2.631±0.00 5.881±4.30 20.407±0.91 22.804±18.35 5.058±4.49 5.461±4.89 24.234±6.91 90.081±80.56 11.590±0.51 61.442±59.29 25.888±4.30 8.735±8.03

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007YS CIL_0007YS_0001 VISTA 17:77940736-78544976
CIL_0003UD CIL_0003UD_0002 CGP 17:78356778-78425114

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001932 IEA regulation of protein phosphorylation
GO:0004860 TAS protein kinase inhibitor activity
GO:0005515 IPI protein binding
GO:0005829 TAS cytosol
GO:0006469 TAS negative regulation of protein kinase activity
GO:0007259 TAS JAK-STAT cascade
GO:0009968 IEA negative regulation of signal transduction
GO:0016567 IEA protein ubiquitination
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0035556 IEA intracellular signal transduction
GO:0040008 IEA regulation of growth
GO:0043066 IEA negative regulation of apoptotic process
GO:0045595 IEA regulation of cell differentiation
GO:0045597 IEA positive regulation of cell differentiation
GO:0046627 IEA negative regulation of insulin receptor signaling pathway
GO:0050728 IEA negative regulation of inflammatory response
GO:0060333 TAS interferon-gamma-mediated signaling pathway
GO:0060334 TAS regulation of interferon-gamma-mediated signaling pathway
GO:0060337 TAS type I interferon signaling pathway
GO:0060338 TAS regulation of type I interferon-mediated signaling pathway
GO:0060397 TAS JAK-STAT cascade involved in growth hormone signaling pathway
GO:0060670 IEA branching involved in labyrinthine layer morphogenesis
GO:0060674 IEA placenta blood vessel development
GO:0060707 IEA trophoblast giant cell differentiation
GO:0060708 IEA spongiotrophoblast differentiation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000054002 Socs3-001 protein_coding Mus_musculus 0 1199

Loading