C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: ArfGAP with dual PH domains 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000330889 ADAP2-001 ENSG00000184060 9606 + 17:30921680-30959322 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonKidneyLiverLungMuscleOvaryPlacentaTestisENST00000330889
Transcript ID Adipose Adrenal Brain Breast Colon Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000330889 2.398±0.00 4.785±0.00 1.515±0.00 2.508±0.47 1.155±0.31 3.741±0.00 1.695±0.00 1.830±1.24 0.248±0.00 1.740±0.44 8.023±0.76 1.514±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004GS CIL_0004GS_0002 CGP 17:30831970-30906820
CIL_000740 CIL_000740_0001 CGP 17:30897336-30959322
CIL_00073Y CIL_00073Y_0001 CGP 17:30906344-30999911

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005546 ISS phosphatidylinositol-4,5-bisphosphate binding
GO:0005547 IDA phosphatidylinositol-3,4,5-trisphosphate binding
GO:0005737 IDA cytoplasm
GO:0005740 ISS mitochondrial envelope
GO:0005886 IDA plasma membrane
GO:0007507 IEP heart development
GO:0008060 IEA ARF GTPase activator activity
GO:0008270 IEA zinc ion binding
GO:0030674 NAS protein binding, bridging
GO:0032312 IEA regulation of ARF GTPase activity
GO:0043325 ISS phosphatidylinositol-3,4-bisphosphate binding
GO:0043533 IDA inositol 1,3,4,5 tetrakisphosphate binding
GO:0043547 IEA positive regulation of GTPase activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000021050 Adap2-001 protein_coding Mus_musculus 0 1317
ENSMUST00000134118 Adap2-002 nonsense_mediated_decay Mus_musculus 0 505

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