C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: tyrosine kinase, non-receptor, 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000333602 TNK2-002 ENSG00000061938 9606 - 3:195863364-195909084 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartLiverOvaryPlacentaTestisENST00000333602
Transcript ID Adipose Adrenal Brain Breast Colon Heart Liver Ovary Placenta Testis
ENST00000333602 2.666±0.00 3.906±0.00 6.744±5.53 1.979±0.00 5.160±0.00 0.632±0.59 1.351±0.00 4.438±0.00 1.874±0.00 2.615±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008QR CIL_0008QR_0001 VISTA 3:195819501-196421470
CIL_0003O7 CIL_0003O7_0002 CGP 3:195863364-196082189

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004712 IDA protein serine/threonine/tyrosine kinase activity
GO:0004713 IDA:IEA protein tyrosine kinase activity
GO:0004715 IEA non-membrane spanning protein tyrosine kinase activity
GO:0005095 TAS GTPase inhibitor activity
GO:0005154 IDA epidermal growth factor receptor binding
GO:0005515 IPI:IEA protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005768 ISS endosome
GO:0005886 IDA plasma membrane
GO:0005905 IDA coated pit
GO:0006468 IEA protein phosphorylation
GO:0006897 IEA endocytosis
GO:0007166 TAS cell surface receptor signaling pathway
GO:0007264 TAS small GTPase mediated signal transduction
GO:0016020 IDA membrane
GO:0016310 IDA phosphorylation
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0030054 IEA cell junction
GO:0030136 IDA clathrin-coated vesicle
GO:0043086 TAS negative regulation of catalytic activity
GO:0046872 IEA metal ion binding
GO:0050699 ISS WW domain binding
GO:0050731 IDA positive regulation of peptidyl-tyrosine phosphorylation
GO:0070436 IDA Grb2-EGFR complex
GO:2000369 IDA regulation of clathrin-mediated endocytosis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000115123 Tnk2-003 protein_coding Mus_musculus 0 3862
ENSMUST00000115125 Tnk2-005 protein_coding Mus_musculus 0 3502
ENSMUST00000115120 Tnk2-004 protein_coding Mus_musculus 0 2222
ENSMUST00000115124 Tnk2-001 protein_coding Mus_musculus 0 2122
ENSMUST00000115126 Tnk2-002 protein_coding Mus_musculus 0 2122
ENSMUST00000137044 Tnk2-013 processed_transcript Mus_musculus 0 1205
ENSDART00000110284 tnk2b-201 protein_coding Danio_rerio 0 904
ENSDART00000123302 tnk2b-202 protein_coding Danio_rerio 0 904
ENSMUST00000152361 Tnk2-008 protein_coding Mus_musculus 0 841
ENSMUST00000115121 Tnk2-016 protein_coding Mus_musculus 0 689
ENSDART00000148745 tnk2b-001 protein_coding Danio_rerio 0 215
ENSDART00000155358 tnk2b-002 retained_intron Danio_rerio 8e-40 171

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