C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: ret proto-oncogene
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000340058 RET-002 ENSG00000165731 9606 + 10:43077079-43127504 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainBreastColonHeartKidneyLiverMuscleOvaryPlacentaTestisENST00000340058
Transcript ID Adipose Brain Breast Colon Heart Kidney Liver Muscle Ovary Placenta Testis
ENST00000340058 0.039±0.00 0.408±0.19 0.146±0.06 0.553±0.45 0.130±0.07 0.054±0.00 0.801±0.61 0.060±0.00 0.184±0.02 0.393±0.16 0.803±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004713 TAS:IEA protein tyrosine kinase activity
GO:0004714 IEA transmembrane receptor protein tyrosine kinase activity
GO:0004872 TAS receptor activity
GO:0005509 IDA:IEA calcium ion binding
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005887 IDA integral component of plasma membrane
GO:0006468 TAS:IEA protein phosphorylation
GO:0006919 IMP activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007156 IEA homophilic cell adhesion via plasma membrane adhesion molecules
GO:0007158 IMP neuron cell-cell adhesion
GO:0007165 TAS signal transduction
GO:0007497 TAS posterior midgut development
GO:0010008 IDA endosome membrane
GO:0010976 IMP positive regulation of neuron projection development
GO:0016020 IEA membrane
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0030155 IDA regulation of cell adhesion
GO:0030335 IDA positive regulation of cell migration
GO:0033619 IDA membrane protein proteolysis
GO:0033630 IDA positive regulation of cell adhesion mediated by integrin
GO:0043235 IDA receptor complex
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0048265 ISS response to pain
GO:0061146 ISS Peyer's patch morphogenesis
GO:0071300 IMP cellular response to retinoic acid
GO:0072300 ISS positive regulation of metanephric glomerulus development
GO:0097021 ISS lymphocyte migration into lymphoid organs
GO:2001241 IMP positive regulation of extrinsic apoptotic signaling pathway in absence of ligand

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000088790 Ret-202 protein_coding Mus_musculus 0 3081
ENSMUST00000032201 Ret-201 protein_coding Mus_musculus 0 2824
ENSDART00000139237 ret-002 protein_coding Danio_rerio 0 791

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