C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: discs, large homolog 1 (Drosophila)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000346964 DLG1-001 ENSG00000075711 9606 - 3:197042560-197298576 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderMuscleOvaryPlacentaTestisENST00000346964
Transcript ID Adipose Adrenal Bladder Muscle Ovary Placenta Testis
ENST00000346964 1.714±0.00 0.998±0.00 1.714±0.00 2.696±0.00 2.355±0.32 2.707±0.00 4.080±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001657 IEA ureteric bud development
GO:0001658 IEA branching involved in ureteric bud morphogenesis
GO:0001771 IEA immunological synapse formation
GO:0001772 TAS immunological synapse
GO:0001935 IDA endothelial cell proliferation
GO:0002088 IEA lens development in camera-type eye
GO:0002369 IEA T cell cytokine production
GO:0004385 TAS guanylate kinase activity
GO:0004721 TAS phosphoprotein phosphatase activity
GO:0005515 IPI:IEA protein binding
GO:0005605 IEA basal lamina
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005783 IDA endoplasmic reticulum
GO:0005794 IDA Golgi apparatus
GO:0005829 TAS cytosol
GO:0005874 IDA microtubule
GO:0005886 TAS plasma membrane
GO:0005911 IDA cell-cell junction
GO:0005923 IDA tight junction
GO:0007015 IDA actin filament organization
GO:0007093 NAS mitotic cell cycle checkpoint
GO:0007163 TAS establishment or maintenance of cell polarity
GO:0007268 TAS synaptic transmission
GO:0007411 TAS axon guidance
GO:0008022 IPI protein C-terminus binding
GO:0008092 TAS cytoskeletal protein binding
GO:0008104 IEA protein localization
GO:0008284 IEA positive regulation of cell proliferation
GO:0009898 IDA cytoplasmic side of plasma membrane
GO:0014069 IEA postsynaptic density
GO:0014704 TAS intercalated disc
GO:0015459 NAS potassium channel regulator activity
GO:0016032 IEA viral process
GO:0016311 TAS dephosphorylation
GO:0016323 IDA basolateral plasma membrane
GO:0016328 IEA lateral plasma membrane
GO:0016337 IDA single organismal cell-cell adhesion
GO:0019901 IPI protein kinase binding
GO:0019902 IPI phosphatase binding
GO:0030054 IDA cell junction
GO:0030432 IEA peristalsis
GO:0030838 IEA positive regulation of actin filament polymerization
GO:0030866 IDA cortical actin cytoskeleton organization
GO:0031253 IEA cell projection membrane
GO:0031434 IPI mitogen-activated protein kinase kinase binding
GO:0031579 IEA membrane raft organization
GO:0031594 IEA neuromuscular junction
GO:0031641 IEA regulation of myelination
GO:0032147 IEA activation of protein kinase activity
GO:0032947 IEA protein complex scaffold
GO:0033268 IEA node of Ranvier
GO:0035748 IEA myelin sheath abaxonal region
GO:0042110 IEA T cell activation
GO:0042130 IEA negative regulation of T cell proliferation
GO:0042391 IDA regulation of membrane potential
GO:0042982 IEA amyloid precursor protein metabolic process
GO:0043219 IEA lateral loop
GO:0043268 IDA positive regulation of potassium ion transport
GO:0044325 IPI ion channel binding
GO:0045121 IEA membrane raft
GO:0045202 IEA synapse
GO:0045211 IEA postsynaptic membrane
GO:0045930 IMP negative regulation of mitotic cell cycle
GO:0046939 TAS nucleotide phosphorylation
GO:0048471 IDA perinuclear region of cytoplasm
GO:0048608 IEA reproductive structure development
GO:0048704 IEA embryonic skeletal system morphogenesis
GO:0048729 IEA tissue morphogenesis
GO:0048745 IEA smooth muscle tissue development
GO:0050680 IEA negative regulation of epithelial cell proliferation
GO:0051898 IEA negative regulation of protein kinase B signaling
GO:0060022 IEA hard palate development
GO:0070062 IDA extracellular vesicular exosome
GO:0070830 IDA tight junction assembly
GO:0072659 IMP protein localization to plasma membrane
GO:0090004 IDA positive regulation of establishment of protein localization to plasma membrane
GO:0097016 IPI L27 domain binding
GO:0097025 IDA MPP7-DLG1-LIN7 complex
GO:1902305 TAS regulation of sodium ion transmembrane transport

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000064477 Dlg1-003 protein_coding Mus_musculus 0 4032
ENSMUST00000115205 Dlg1-002 protein_coding Mus_musculus 0 2627
ENSMUST00000100001 Dlg1-201 protein_coding Mus_musculus 0 2623
ENSMUST00000115201 Dlg1-007 protein_coding Mus_musculus 0 2623
ENSMUST00000115196 Dlg1-006 protein_coding Mus_musculus 0 1929
ENSMUST00000023454 Dlg1-004 protein_coding Mus_musculus 0 1818
ENSMUST00000132176 Dlg1-001 nonsense_mediated_decay Mus_musculus 0 1242
ENSMUST00000131136 Dlg1-005 protein_coding Mus_musculus 0 859
ENSMUST00000138213 Dlg1-013 retained_intron Mus_musculus 0 547
ENSDART00000024906 dlg1-201 protein_coding Danio_rerio 0 545
ENSMUST00000130920 Dlg1-010 nonsense_mediated_decay Mus_musculus 0 501
ENSMUST00000113735 Dlg3-004 protein_coding Mus_musculus 0 483
ENSMUST00000147863 Dlg3-002 retained_intron Mus_musculus 0 483
ENSDART00000028406 dlg1-001 protein_coding Danio_rerio 0 435
ENSDART00000148773 dlg1l-005 protein_coding Danio_rerio 0 433
ENSMUST00000155958 Dlg1-008 retained_intron Mus_musculus 0 355
ENSMUST00000147382 Dlg1-012 processed_transcript Mus_musculus 0 337
ENSMUST00000155847 Dlg1-011 retained_intron Mus_musculus 0 324
ENSMUST00000087984 Dlg3-003 protein_coding Mus_musculus 0 316
ENSMUST00000113736 Dlg3-001 protein_coding Mus_musculus 0 316
ENSMUST00000000901 Dlg3-006 protein_coding Mus_musculus 0 316
ENSMUST00000140258 Dlg1-014 retained_intron Mus_musculus 0 272
ENSDART00000148895 dlg1l-004 processed_transcript Danio_rerio 0 204
ENSDART00000137198 dlg1-005 processed_transcript Danio_rerio 7e-36 158
ENSDART00000132170 dlg1-003 processed_transcript Danio_rerio 7e-21 108

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