C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: discs, large homolog 1 (Drosophila)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000064477 Dlg1-003 ENSMUSG00000022770 10090 + 16:31664039-31873346 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000064477
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000064477 4.665±2.47 10.572±3.93 17.331±1.05 3.956±0.73 4.141±1.53 3.936±1.40 8.400±1.38 4.722±2.24 4.550±2.02 8.557±1.20 8.099±2.41 5.148±1.70 11.193±2.92 1.623±0.76

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003W7 CIL_0003W7_0002 CGP 16:31663443-31899020

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001657 IMP ureteric bud development
GO:0001658 IMP branching involved in ureteric bud morphogenesis
GO:0001771 IMP immunological synapse formation
GO:0001772 IDA immunological synapse
GO:0001935 ISS endothelial cell proliferation
GO:0002088 IMP lens development in camera-type eye
GO:0002369 IMP T cell cytokine production
GO:0005515 IPI protein binding
GO:0005605 IDA basal lamina
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005783 IEA endoplasmic reticulum
GO:0005794 IEA Golgi apparatus
GO:0005874 IEA microtubule
GO:0005886 IDA plasma membrane
GO:0005911 IEA cell-cell junction
GO:0005913 TAS cell-cell adherens junction
GO:0005923 IEA tight junction
GO:0007015 ISS actin filament organization
GO:0008022 IEA protein C-terminus binding
GO:0008104 IGI protein localization
GO:0008284 IMP positive regulation of cell proliferation
GO:0009898 IEA cytoplasmic side of plasma membrane
GO:0014069 IDA postsynaptic density
GO:0016323 ISS basolateral plasma membrane
GO:0016328 IDA lateral plasma membrane
GO:0016337 ISS single organismal cell-cell adhesion
GO:0019901 ISS protein kinase binding
GO:0019902 ISS phosphatase binding
GO:0030054 IDA cell junction
GO:0030432 IMP peristalsis
GO:0030838 IMP positive regulation of actin filament polymerization
GO:0030866 ISS cortical actin cytoskeleton organization
GO:0031253 IDA cell projection membrane
GO:0031434 IEA mitogen-activated protein kinase kinase binding
GO:0031579 IMP membrane raft organization
GO:0031594 IDA neuromuscular junction
GO:0031641 IMP regulation of myelination
GO:0032147 IMP activation of protein kinase activity
GO:0032947 IMP protein complex scaffold
GO:0033268 IDA node of Ranvier
GO:0035748 IDA myelin sheath abaxonal region
GO:0040018 TAS positive regulation of multicellular organism growth
GO:0042110 IMP T cell activation
GO:0042130 IMP negative regulation of T cell proliferation
GO:0042391 IGI regulation of membrane potential
GO:0042982 IGI amyloid precursor protein metabolic process
GO:0043219 IDA lateral loop
GO:0043268 IEA positive regulation of potassium ion transport
GO:0044325 IEA ion channel binding
GO:0045121 IDA membrane raft
GO:0045202 IDA synapse
GO:0045211 IEA postsynaptic membrane
GO:0045930 ISS negative regulation of mitotic cell cycle
GO:0048471 IEA perinuclear region of cytoplasm
GO:0048608 IMP reproductive structure development
GO:0048639 TAS positive regulation of developmental growth
GO:0048704 IMP embryonic skeletal system morphogenesis
GO:0048729 IMP tissue morphogenesis
GO:0048745 IMP smooth muscle tissue development
GO:0050680 IMP negative regulation of epithelial cell proliferation
GO:0051898 IMP negative regulation of protein kinase B signaling
GO:0060022 IMP hard palate development
GO:0070062 IEA extracellular vesicular exosome
GO:0070830 IEA tight junction assembly
GO:0072659 IEA protein localization to plasma membrane
GO:0090004 IEA positive regulation of establishment of protein localization to plasma membrane
GO:0097016 IEA L27 domain binding
GO:0097025 IEA MPP7-DLG1-LIN7 complex

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000024906 dlg1-201 protein_coding Danio_rerio 0 582
ENSDART00000028406 dlg1-001 protein_coding Danio_rerio 0 479
ENSDART00000148733 dlg1l-002 nonsense_mediated_decay Danio_rerio 0 446
ENSDART00000061429 dlg1l-006 protein_coding Danio_rerio 0 446
ENSDART00000148773 dlg1l-005 protein_coding Danio_rerio 0 420
ENSDART00000043795 dlg1l-001 protein_coding Danio_rerio 0 398
ENSDART00000148895 dlg1l-004 processed_transcript Danio_rerio 2.94273e-44 185
ENSDART00000137198 dlg1-005 processed_transcript Danio_rerio 6e-36 158
ENSDART00000132170 dlg1-003 processed_transcript Danio_rerio 1e-22 113
ENST00000346964 DLG1-001 protein_coding Homo_sapiens 0 4032
ENST00000357674 DLG1-201 protein_coding Homo_sapiens 0 3208
ENST00000392380 DLG1-003 protein_coding Homo_sapiens 0 885
ENST00000392381 DLG1-006 nonsense_mediated_decay Homo_sapiens 0 2697
ENST00000392382 DLG1-013 protein_coding Homo_sapiens 0 1818
ENST00000412364 DLG1-002 protein_coding Homo_sapiens 0 483
ENST00000419227 DLG1-018 nonsense_mediated_decay Homo_sapiens 0 874
ENST00000419354 DLG1-008 protein_coding Homo_sapiens 0 2621
ENST00000419553 DLG1-009 protein_coding Homo_sapiens 0 665
ENST00000422288 DLG1-019 protein_coding Homo_sapiens 0 1748
ENST00000434148 DLG1-004 protein_coding Homo_sapiens 0 207
ENST00000436682 DLG1-005 protein_coding Homo_sapiens 0 536
ENST00000443183 DLG1-020 protein_coding Homo_sapiens 0 1823
ENST00000447466 DLG1-021 protein_coding Homo_sapiens 0 970
ENST00000448528 DLG1-007 protein_coding Homo_sapiens 0 2623
ENST00000450955 DLG1-027 protein_coding Homo_sapiens 0 2898
ENST00000452595 DLG1-011 protein_coding Homo_sapiens 0 1823
ENST00000453607 DLG1-024 protein_coding Homo_sapiens 0 261
ENST00000456699 DLG1-023 protein_coding Homo_sapiens 0 721
ENST00000469371 DLG1-012 retained_intron Homo_sapiens 0 1170
ENST00000470629 DLG1-026 retained_intron Homo_sapiens 0 298
ENST00000471733 DLG1-017 retained_intron Homo_sapiens 0 1818
ENST00000475394 DLG1-016 retained_intron Homo_sapiens 0 477
ENST00000477312 DLG1-014 retained_intron Homo_sapiens 0 669
ENST00000485409 DLG1-010 processed_transcript Homo_sapiens 0 617
ENST00000486877 DLG1-022 retained_intron Homo_sapiens 0 505

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