C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000347454 EIF2B4-001 ENSG00000115211 9606 - 2:27364352-27370486 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainColonMuscleOvaryPlacentaTestisENST00000347454
Transcript ID Adipose Brain Colon Muscle Ovary Placenta Testis
ENST00000347454 9.386±0.00 12.330±0.00 14.946±0.00 10.889±0.00 11.432±0.00 12.131±3.81 24.076±3.86

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001DH CIL_0001DH_0001 CGP 2:27325849-27370486
CIL_000133 CIL_000133_0001 CGP 2:27364352-27377533

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001541 IMP ovarian follicle development
GO:0003743 IDA translation initiation factor activity
GO:0005085 IDA guanyl-nucleotide exchange factor activity
GO:0005515 IPI protein binding
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0005851 IDA eukaryotic translation initiation factor 2B complex
GO:0006412 TAS translation
GO:0006413 IDA translational initiation
GO:0006417 NAS regulation of translation
GO:0006446 IBA regulation of translational initiation
GO:0009408 ISS response to heat
GO:0009749 ISS response to glucose
GO:0010467 TAS gene expression
GO:0014003 IMP oligodendrocyte development
GO:0031369 ISS translation initiation factor binding
GO:0032057 ISS negative regulation of translational initiation in response to stress
GO:0042552 IMP myelination
GO:0043434 ISS response to peptide hormone
GO:0043547 IDA positive regulation of GTPase activity
GO:0044237 IEA cellular metabolic process
GO:0044267 TAS cellular protein metabolic process
GO:0045947 IBA negative regulation of translational initiation
GO:0051716 IDA cellular response to stimulus

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000077693 Eif2b4-001 protein_coding Mus_musculus 0 1797
ENSMUST00000114605 Eif2b4-003 protein_coding Mus_musculus 0 1746
ENSMUST00000166769 Eif2b4-201 protein_coding Mus_musculus 0 1738
ENSMUST00000114603 Eif2b4-002 protein_coding Mus_musculus 0 1735
ENSMUST00000153986 Eif2b4-007 retained_intron Mus_musculus 0 558
ENSMUST00000130667 Eif2b4-008 processed_transcript Mus_musculus 0 527
ENSMUST00000139216 Eif2b4-005 processed_transcript Mus_musculus 0 422
ENSMUST00000128037 Eif2b4-006 protein_coding Mus_musculus 0 396

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