C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: T-box 5
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000349716 TBX5-003 ENSG00000089225 9606 - 12:114353931-114408387 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainBreastLungMuscleOvaryENST00000349716
Transcript ID Adipose Brain Breast Lung Muscle Ovary
ENST00000349716 0.132±0.00 0.042±0.00 0.035±0.00 1.467±0.00 0.060±0.00 0.089±0.04

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008CB CIL_0008CB_0001 VISTA 12:113922562-114523201
CIL_00095S CIL_00095S_0001 VISTA 12:114119731-114721669
CIL_00092A CIL_00092A_0001 VISTA 12:114147407-114748589

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003218 ISS cardiac left ventricle formation
GO:0003281 ISS ventricular septum development
GO:0003677 IDA DNA binding
GO:0003700 IDA:IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA:IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006367 TAS transcription initiation from RNA polymerase II promoter
GO:0007267 IDA cell-cell signaling
GO:0007507 IDA heart development
GO:0008134 IPI transcription factor binding
GO:0008285 IDA negative regulation of cell proliferation
GO:0010467 TAS gene expression
GO:0010719 TAS negative regulation of epithelial to mesenchymal transition
GO:0030262 IDA apoptotic nuclear changes
GO:0030326 IMP embryonic limb morphogenesis
GO:0030336 IDA negative regulation of cell migration
GO:0035115 IMP embryonic forelimb morphogenesis
GO:0035136 IMP forelimb morphogenesis
GO:0043565 IDA sequence-specific DNA binding
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0051891 IDA positive regulation of cardioblast differentiation
GO:0060039 IDA pericardium development
GO:0060044 IDA negative regulation of cardiac muscle cell proliferation
GO:0060980 TAS cell migration involved in coronary vasculogenesis
GO:1900117 IC regulation of execution phase of apoptosis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000018407 Tbx5-201 protein_coding Mus_musculus 0 193

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