C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: ATR serine/threonine kinase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000350721 ATR-001 ENSG00000175054 9606 - 3:142449237-142578826 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000350721
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000350721 0.936±0.00 2.225±0.00 1.380±0.00 1.837±0.54 0.702±0.00 1.896±1.46 0.609±0.04 0.753±0.00 1.954±1.50 0.739±0.00 0.324±0.00 1.664±0.99 0.522±0.39 1.021±0.12

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000077 IDA DNA damage checkpoint
GO:0001741 IEA XY body
GO:0003677 IEA DNA binding
GO:0004672 IDA protein kinase activity
GO:0004674 IDA:IEA protein serine/threonine kinase activity
GO:0005488 IEA binding
GO:0005515 IPI:IEA protein binding
GO:0005524 IEA ATP binding
GO:0005654 TAS nucleoplasm
GO:0005694 ISS chromosome
GO:0006260 TAS DNA replication
GO:0006281 TAS DNA repair
GO:0006468 IEA protein phosphorylation
GO:0006974 TAS cellular response to DNA damage stimulus
GO:0007049 TAS cell cycle
GO:0007275 TAS multicellular organismal development
GO:0008156 IMP negative regulation of DNA replication
GO:0016605 IDA PML body
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0016773 IEA phosphotransferase activity, alcohol group as acceptor
GO:0018105 IDA peptidyl-serine phosphorylation
GO:0032405 IDA MutLalpha complex binding
GO:0032407 IDA MutSalpha complex binding
GO:0034644 IMP cellular response to UV
GO:0042493 IEA response to drug
GO:0043393 IEA regulation of protein binding
GO:0043517 IMP positive regulation of DNA damage response, signal transduction by p53 class mediator
GO:0046777 IDA protein autophosphorylation
GO:0071480 IDA cellular response to gamma radiation
GO:0090399 IMP replicative senescence

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000034980 Atr-001 protein_coding Mus_musculus 0 9588
ENSMUST00000185473 Atr-002 retained_intron Mus_musculus 0 3805
ENSMUST00000186524 Atr-012 retained_intron Mus_musculus 0 514
ENSMUST00000188164 Atr-011 retained_intron Mus_musculus 0 313
ENSMUST00000186997 Atr-003 retained_intron Mus_musculus 0 302
ENSMUST00000186127 Atr-007 retained_intron Mus_musculus 1e-35 158
ENSMUST00000188088 Atr-009 retained_intron Mus_musculus 9e-32 145

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