C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: activin A receptor, type IIB
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000352511 ACVR2B-001 ENSG00000114739 9606 + 3:38453851-38493142 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000352511
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000352511 1.027±0.00 0.346±0.00 0.646±0.50 0.950±0.28 0.636±0.00 0.436±0.27 0.446±0.34 0.710±0.05 0.458±0.30 1.044±0.72 0.868±0.41 1.076±0.48 2.298±0.38

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008BE CIL_0008BE_0001 VISTA 3:38261144-38866061
CIL_0005W6 CIL_0005W6_0001 CGP 3:38346760-38493142
CIL_0005W0 CIL_0005W0_0001 CGP 3:38453851-38542161

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001501 IEA skeletal system development
GO:0001702 IEA gastrulation with mouth forming second
GO:0001822 IEA kidney development
GO:0001946 ISS lymphangiogenesis
GO:0001974 ISS blood vessel remodeling
GO:0004672 IEA protein kinase activity
GO:0004674 IMP protein serine/threonine kinase activity
GO:0004675 IEA transmembrane receptor protein serine/threonine kinase activity
GO:0004702 IEA receptor signaling protein serine/threonine kinase activity
GO:0004712 IEA protein serine/threonine/tyrosine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005024 IEA transforming growth factor beta-activated receptor activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005737 IDA cytoplasm
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0006468 IEA protein phosphorylation
GO:0007165 IDA signal transduction
GO:0007178 TAS transmembrane receptor protein serine/threonine kinase signaling pathway
GO:0007368 IEA determination of left/right symmetry
GO:0007389 IEA pattern specification process
GO:0007498 IEA mesoderm development
GO:0007507 IEA heart development
GO:0009749 IEA response to glucose
GO:0009791 IEA post-embryonic development
GO:0009952 IMP anterior/posterior pattern specification
GO:0009966 IEA regulation of signal transduction
GO:0016020 IEA membrane
GO:0016362 TAS activin receptor activity, type II
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0019838 IPI growth factor binding
GO:0023014 IEA signal transduction by phosphorylation
GO:0030073 IEA insulin secretion
GO:0030324 IEA lung development
GO:0030501 IMP positive regulation of bone mineralization
GO:0030509 IDA BMP signaling pathway
GO:0031016 IEA pancreas development
GO:0032147 IEA activation of protein kinase activity
GO:0032924 TAS activin receptor signaling pathway
GO:0032927 IDA positive regulation of activin receptor signaling pathway
GO:0034711 IEA inhibin binding
GO:0035265 IEA organ growth
GO:0042475 IEA odontogenesis of dentin-containing tooth
GO:0043234 IPI protein complex
GO:0045669 IMP positive regulation of osteoblast differentiation
GO:0046872 IEA metal ion binding
GO:0048185 IEA activin binding
GO:0048617 IEA embryonic foregut morphogenesis
GO:0048705 IEA skeletal system morphogenesis
GO:0060021 IEA palate development
GO:0060836 ISS lymphatic endothelial cell differentiation
GO:0060840 ISS artery development
GO:0060841 ISS venous blood vessel development
GO:0061298 ISS retina vasculature development in camera-type eye

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000165044 Acvr2b-202 protein_coding Mus_musculus 0 1439
ENSMUST00000035093 Acvr2b-201 protein_coding Mus_musculus 0 1439

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