C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: cytochrome P450, family 2, subfamily D, polypeptide 6
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000359033 CYP2D6-002 ENSG00000100197 9606 - 22:42126556-42130865 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverLungTestisENST00000359033
Transcript ID Brain Heart Kidney Liver Lung Testis
ENST00000359033 0.261±0.00 0.142±0.00 25.317±0.00 32.943±0.00 0.393±0.00 0.261±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004BK CIL_0004BK_0001 CGP 22:42085525-42130906
CIL_0004LO CIL_0004LO_0001 CGP 22:42126499-42343616

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004497 IDA monooxygenase activity
GO:0005506 IEA iron ion binding
GO:0005739 IDA mitochondrion
GO:0005783 TAS endoplasmic reticulum
GO:0005789 TAS endoplasmic reticulum membrane
GO:0006805 TAS xenobiotic metabolic process
GO:0008144 IDA drug binding
GO:0008202 IMP steroid metabolic process
GO:0009804 IDA coumarin metabolic process
GO:0009820 IDA alkaloid metabolic process
GO:0009822 IDA alkaloid catabolic process
GO:0016098 IDA monoterpenoid metabolic process
GO:0016491 IDA oxidoreductase activity
GO:0016705 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0017144 IMP drug metabolic process
GO:0020037 IDA:IEA heme binding
GO:0033076 IDA isoquinoline alkaloid metabolic process
GO:0042737 IDA drug catabolic process
GO:0044281 TAS small molecule metabolic process
GO:0046483 IDA heterocycle metabolic process
GO:0051100 IDA negative regulation of binding
GO:0055114 IDA:IEA oxidation-reduction process
GO:0070330 IEA aromatase activity
GO:0070989 IDA oxidative demethylation
GO:0090350 IDA negative regulation of cellular organofluorine metabolic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000023083 Cyp2d22-201 protein_coding Mus_musculus 0 874
ENSMUST00000072776 Cyp2d10-201 protein_coding Mus_musculus 0 721
ENSMUST00000170255 Cyp2d11-201 protein_coding Mus_musculus 0 702
ENSMUST00000006094 Cyp2d26-201 protein_coding Mus_musculus 0 701
ENSMUST00000068861 Cyp2d12-201 protein_coding Mus_musculus 0 676
ENSMUST00000089129 Cyp2d9-201 protein_coding Mus_musculus 0 676
ENSMUST00000109515 Cyp2d34-201 protein_coding Mus_musculus 0 649
ENSMUST00000180453 Cyp2d41-ps-001 unprocessed_pseudogene Mus_musculus 0 617
ENSMUST00000055721 Cyp2d40-201 protein_coding Mus_musculus 0 614

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