C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: DNA (cytosine-5-)-methyltransferase 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000359526 DNMT1-002 ENSG00000130816 9606 - 19:10133540-10195079 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000359526
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000359526 3.541±0.00 3.512±0.00 2.921±0.00 1.207±0.00 2.215±0.00 1.070±0.00 1.580±0.00 0.838±0.00 3.035±0.00 4.954±3.52 9.167±4.35 7.928±0.09

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004BQ CIL_0004BQ_0002 CGP 19:10115017-10231286
CIL_000773 CIL_000773_0002 CGP 19:10133345-10231286

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0000792 IEA heterochromatin
GO:0003677 IDA:IEA DNA binding
GO:0003682 IEA chromatin binding
GO:0003723 IEA RNA binding
GO:0003886 IDA:IEA DNA (cytosine-5-)-methyltransferase activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005657 IEA replication fork
GO:0005721 IEA pericentric heterochromatin
GO:0006306 TAS DNA methylation
GO:0006351 IEA transcription, DNA-templated
GO:0008134 IEA transcription factor binding
GO:0008168 IEA methyltransferase activity
GO:0008270 IEA zinc ion binding
GO:0008327 IEA methyl-CpG binding
GO:0009008 IDA DNA-methyltransferase activity
GO:0010216 IDA maintenance of DNA methylation
GO:0010468 IEA regulation of gene expression
GO:0010628 IMP positive regulation of gene expression
GO:0016458 IEA gene silencing
GO:0016568 IEA chromatin modification
GO:0042127 IEA regulation of cell proliferation
GO:0045892 IEA negative regulation of transcription, DNA-templated
GO:0051571 IMP positive regulation of histone H3-K4 methylation
GO:0051573 IMP negative regulation of histone H3-K9 methylation
GO:0071230 IEA cellular response to amino acid stimulus
GO:0090116 IEA C-5 methylation of cytosine

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000178110 Dnmt1-203 protein_coding Mus_musculus 0 3103
ENSMUST00000004202 Dnmt1-201 protein_coding Mus_musculus 0 3103
ENSMUST00000177754 Dnmt1-202 protein_coding Mus_musculus 0 3103

Loading