C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: transglutaminase 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000361475 TGM2-002 ENSG00000198959 9606 - 20:38127387-38165372 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainBreastColonLiverLungOvaryPlacentaENST00000361475
Transcript ID Bladder Brain Breast Colon Liver Lung Ovary Placenta
ENST00000361475 2.829±0.00 0.765±0.00 5.964±0.00 1.176±0.00 9.100±0.00 8.962±0.00 5.246±0.57 157.247±73.44

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004NX CIL_0004NX_0001 CGP 20:37983007-38127780
CIL_0004NY CIL_0004NY_0001 CGP 20:38033546-38166578
CIL_0004NZ CIL_0004NZ_0001 CGP 20:38127387-38260772

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001974 IEA blood vessel remodeling
GO:0003810 ISS:IEA protein-glutamine gamma-glutamyltransferase activity
GO:0005515 IPI protein binding
GO:0005525 IEA GTP binding
GO:0005737 IEA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005829 IDA cytosol
GO:0005886 IEA plasma membrane
GO:0005925 IDA focal adhesion
GO:0007200 IEA phospholipase C-activating G-protein coupled receptor signaling pathway
GO:0018149 IEA peptide cross-linking
GO:0018153 IEA isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine
GO:0019904 IEA protein domain specific binding
GO:0032471 IMP negative regulation of endoplasmic reticulum calcium ion concentration
GO:0043065 IMP positive regulation of apoptotic process
GO:0043123 IEA positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043277 IDA apoptotic cell clearance
GO:0045785 ISS positive regulation of cell adhesion
GO:0046872 IEA metal ion binding
GO:0048661 IEA positive regulation of smooth muscle cell proliferation
GO:0050729 IEA positive regulation of inflammatory response
GO:0051260 IEA protein homooligomerization
GO:0051482 IEA positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
GO:0051561 IMP positive regulation of mitochondrial calcium ion concentration
GO:0060445 IEA branching involved in salivary gland morphogenesis
GO:0060662 IEA salivary gland cavitation
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000103122 Tgm2-001 protein_coding Mus_musculus 0 1892
ENSMUST00000174718 Tgm2-004 nonsense_mediated_decay Mus_musculus 0 276

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