C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: cell division cycle 73
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000367435 CDC73-001 ENSG00000134371 9606 + 1:193122017-193253901 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000367435
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000367435 4.061±0.00 2.798±0.00 3.374±0.00 3.577±0.04 4.205±1.17 4.120±1.61 4.367±1.71 3.475±0.84 5.620±4.64 5.494±1.10 1.180±0.02 3.842±0.39 2.675±0.69 3.518±1.37

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005IF CIL_0005IF_0001 CGP 1:193122017-193253901

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0000993 IDA RNA polymerase II core binding
GO:0001711 ISS endodermal cell fate commitment
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006378 IMP mRNA polyadenylation
GO:0007049 IEA cell cycle
GO:0008285 IDA negative regulation of cell proliferation
GO:0010390 IDA histone monoubiquitination
GO:0016055 IEA Wnt signaling pathway
GO:0016593 IDA Cdc73/Paf1 complex
GO:0019827 ISS stem cell maintenance
GO:0030177 IDA positive regulation of Wnt signaling pathway
GO:0031442 IMP positive regulation of mRNA 3'-end processing
GO:0031648 IMP protein destabilization
GO:0032968 IDA positive regulation of transcription elongation from RNA polymerase II promoter
GO:0033523 IDA histone H2B ubiquitination
GO:0045638 IDA negative regulation of myeloid cell differentiation
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0048147 IMP negative regulation of fibroblast proliferation
GO:0050680 IMP negative regulation of epithelial cell proliferation
GO:0071222 ISS cellular response to lipopolysaccharide
GO:2000134 IDA negative regulation of G1/S transition of mitotic cell cycle

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000018337 Cdc73-001 protein_coding Mus_musculus 0 2449
ENSMUST00000162638 Cdc73-002 processed_transcript Mus_musculus 0 952
ENSMUST00000159794 Cdc73-003 nonsense_mediated_decay Mus_musculus 0 366

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