C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: Rho guanine nucleotide exchange factor (GEF) 11
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000368194 ARHGEF11-001 ENSG00000132694 9606 - 1:156934840-157045370 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainBreastHeartLiverMuscleOvaryPlacentaTestisENST00000368194
Transcript ID Adipose Brain Breast Heart Liver Muscle Ovary Placenta Testis
ENST00000368194 1.971±0.00 2.802±0.74 3.016±0.00 1.567±0.00 0.873±0.01 2.321±0.00 3.140±0.43 0.735±0.00 1.982±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000850 CIL_000850_0001 VISTA 1:156360457-156965492

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000910 NAS cytokinesis
GO:0001558 NAS regulation of cell growth
GO:0001664 IDA G-protein coupled receptor binding
GO:0005089 TAS:IEA Rho guanyl-nucleotide exchange factor activity
GO:0005096 IEA GTPase activator activity
GO:0005515 IPI:IEA protein binding
GO:0005622 IC intracellular
GO:0005737 IDA:IEA cytoplasm
GO:0005829 TAS cytosol
GO:0006928 NAS cellular component movement
GO:0006941 NAS striated muscle contraction
GO:0007186 TAS G-protein coupled receptor signaling pathway
GO:0007264 TAS small GTPase mediated signal transduction
GO:0007266 IDA Rho protein signal transduction
GO:0007411 TAS axon guidance
GO:0008277 IEA regulation of G-protein coupled receptor protein signaling pathway
GO:0016020 IEA membrane
GO:0030010 NAS establishment of cell polarity
GO:0030036 NAS actin cytoskeleton organization
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0035023 IEA regulation of Rho protein signal transduction
GO:0038032 IEA termination of G-protein coupled receptor signaling pathway
GO:0043065 TAS positive regulation of apoptotic process
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0051056 TAS regulation of small GTPase mediated signal transduction
GO:0097190 TAS apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000129113 Arhgef11-002 protein_coding Mus_musculus 0 3792
ENSMUST00000039476 Arhgef11-001 protein_coding Mus_musculus 0 2540
ENSMUST00000152006 Arhgef11-003 nonsense_mediated_decay Mus_musculus 0 2359
ENSMUST00000136072 Arhgef11-004 retained_intron Mus_musculus 0 1408
ENSMUST00000142799 Arhgef11-005 retained_intron Mus_musculus 0 944

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