C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000369947 HTR1B-001 ENSG00000135312 9606 - 6:77462205-77463464 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonKidneyLungMuscleOvaryPlacentaTestisENST00000369947
Transcript ID Adipose Bladder Brain Breast Colon Kidney Lung Muscle Ovary Placenta Testis
ENST00000369947 0.112±0.00 0.265±0.00 0.531±0.12 0.701±0.43 0.391±0.06 0.434±0.00 0.186±0.08 0.199±0.00 0.221±0.15 1.515±0.56 0.626±0.19

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006PU CIL_0006PU_0001 CGP 6:75921115-77463464
CIL_0006GC CIL_0006GC_0001 CGP 6:77462205-77926974

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002031 IEA G-protein coupled receptor internalization
GO:0004930 IEA G-protein coupled receptor activity
GO:0004993 IDA serotonin receptor activity
GO:0005737 IEA cytoplasm
GO:0005886 TAS plasma membrane
GO:0005887 IMP integral component of plasma membrane
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0007187 TAS G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
GO:0007198 IDA adenylate cyclase-inhibiting serotonin receptor signaling pathway
GO:0007205 IEA protein kinase C-activating G-protein coupled receptor signaling pathway
GO:0007268 IEA synaptic transmission
GO:0007631 IEA feeding behavior
GO:0008144 IEA drug binding
GO:0014059 IEA regulation of dopamine secretion
GO:0014063 ISS negative regulation of serotonin secretion
GO:0016021 IEA integral component of membrane
GO:0030818 IDA negative regulation of cAMP biosynthetic process
GO:0032229 IEA negative regulation of synaptic transmission, GABAergic
GO:0035690 IDA cellular response to drug
GO:0042220 IEA response to cocaine
GO:0042310 IEA vasoconstriction
GO:0042493 IEA response to drug
GO:0042756 IEA drinking behavior
GO:0045471 IEA response to ethanol
GO:0046849 IEA bone remodeling
GO:0050795 IEA regulation of behavior
GO:0051378 IEA serotonin binding
GO:0051385 IEA response to mineralocorticoid
GO:0051967 IEA negative regulation of synaptic transmission, glutamatergic
GO:0071312 IDA cellular response to alkaloid
GO:0071502 IEA cellular response to temperature stimulus

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000051005 Htr1b-201 protein_coding Mus_musculus 0 1515
ENSMUST00000183482 Htr1b-002 protein_coding Mus_musculus 0 1515

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