C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: ring finger protein 8, E3 ubiquitin protein ligase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000373479 RNF8-001 ENSG00000112130 9606 + 6:37353972-37394738 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartLungMuscleOvaryTestisENST00000373479
Transcript ID Brain Heart Lung Muscle Ovary Testis
ENST00000373479 0.314±0.00 0.230±0.00 0.210±0.00 0.098±0.00 0.685±0.00 0.658±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00089L CIL_00089L_0001 VISTA 6:36799205-37399713
CIL_0005CZ CIL_0005CZ_0001 CGP 6:37257772-37394738
CIL_0001Z5 CIL_0001Z5_0001 CGP 6:37353972-37482827

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000151 IDA ubiquitin ligase complex
GO:0000781 ISS chromosome, telomeric region
GO:0003682 IDA chromatin binding
GO:0004842 IDA ubiquitin-protein transferase activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA:IEA nucleus
GO:0005730 IDA nucleolus
GO:0006302 IDA double-strand break repair
GO:0006303 ISS double-strand break repair via nonhomologous end joining
GO:0006511 IDA ubiquitin-dependent protein catabolic process
GO:0006974 IDA:IEA cellular response to DNA damage stimulus
GO:0007067 IEA mitotic nuclear division
GO:0007286 ISS spermatid development
GO:0008270 IDA:IEA zinc ion binding
GO:0010212 IDA response to ionizing radiation
GO:0016567 IEA protein ubiquitination
GO:0016881 IEA acid-amino acid ligase activity
GO:0031625 IPI ubiquitin protein ligase binding
GO:0033522 IDA histone H2A ubiquitination
GO:0033523 ISS histone H2B ubiquitination
GO:0034244 IMP negative regulation of transcription elongation from RNA polymerase II promoter
GO:0035861 IDA site of double-strand break
GO:0036297 TAS interstrand cross-link repair
GO:0042393 IDA histone binding
GO:0042803 IDA protein homodimerization activity
GO:0043486 ISS histone exchange
GO:0045190 ISS isotype switching
GO:0045739 IDA positive regulation of DNA repair
GO:0046872 IEA metal ion binding
GO:0051301 IEA cell division
GO:0051865 IDA protein autoubiquitination
GO:0070534 IDA protein K63-linked ubiquitination
GO:0070535 IMP histone H2A K63-linked ubiquitination
GO:0070936 IDA protein K48-linked ubiquitination

Homologs

No Homologs available.

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