C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: growth differentiation factor 5
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000374369 GDF5-002 ENSG00000125965 9606 - 20:35433347-35438243 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BreastHeartLungMuscleOvaryTestisENST00000374369
Transcript ID Breast Heart Lung Muscle Ovary Testis
ENST00000374369 0.932±0.71 0.029±0.00 2.374±2.25 0.018±0.00 0.186±0.00 0.827±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008EI CIL_0008EI_0001 VISTA 20:35018152-35620688
CIL_0005FR CIL_0005FR_0001 CGP 20:35302566-35435450
CIL_0005FQ CIL_0005FQ_0001 CGP 20:35433029-35454746
CIL_0002I5 CIL_0002I5_0001 CGP 20:35433347-35519280

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005125 IEA cytokine activity
GO:0005515 IPI protein binding
GO:0005576 TAS extracellular region
GO:0005615 IEA extracellular space
GO:0005886 IEA plasma membrane
GO:0007179 TAS transforming growth factor beta receptor signaling pathway
GO:0007267 TAS cell-cell signaling
GO:0008083 IEA growth factor activity
GO:0030198 TAS extracellular matrix organization
GO:0040007 IEA growth
GO:0042802 IPI identical protein binding
GO:0050680 IDA negative regulation of epithelial cell proliferation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000040162 Gdf5-001 protein_coding Mus_musculus 0 2420
ENSMUST00000109629 Gm15557-001 protein_coding Mus_musculus 0 1260

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