C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: growth differentiation factor 5
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000374372 GDF5-001 ENSG00000125965 9606 - 20:35433347-35454746 protein_coding

Homo sapiens EnsemblGRCh38

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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverOvaryPlacentaTestisENST00000374372
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Ovary Placenta Testis
ENST00000374372 0.276±0.00 0.269±0.00 0.321±0.00 0.273±0.00 0.173±0.00 0.035±0.00 0.030±0.00 0.026±0.00 0.037±0.01 0.024±0.00 0.200±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008EI CIL_0008EI_0001 VISTA 20:35018152-35620688
CIL_0005FR CIL_0005FR_0001 CGP 20:35302566-35435450
CIL_0005FQ CIL_0005FQ_0001 CGP 20:35433029-35454746
CIL_0002I5 CIL_0002I5_0001 CGP 20:35433347-35519280

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002062 IEA chondrocyte differentiation
GO:0005102 IEA receptor binding
GO:0005125 IEA cytokine activity
GO:0005515 IPI protein binding
GO:0005576 TAS extracellular region
GO:0005615 IEA extracellular space
GO:0005886 IEA plasma membrane
GO:0007178 IEA transmembrane receptor protein serine/threonine kinase signaling pathway
GO:0007179 TAS transforming growth factor beta receptor signaling pathway
GO:0007267 TAS cell-cell signaling
GO:0008083 IEA growth factor activity
GO:0030198 TAS extracellular matrix organization
GO:0030326 IEA embryonic limb morphogenesis
GO:0032332 IEA positive regulation of chondrocyte differentiation
GO:0035136 IEA forelimb morphogenesis
GO:0035137 IEA hindlimb morphogenesis
GO:0040007 IEA growth
GO:0040014 IEA regulation of multicellular organism growth
GO:0042802 IPI identical protein binding
GO:0043524 IEA negative regulation of neuron apoptotic process
GO:0045666 IEA positive regulation of neuron differentiation
GO:0050680 IDA negative regulation of epithelial cell proliferation
GO:2001054 IEA negative regulation of mesenchymal cell apoptotic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000040162 Gdf5-001 protein_coding Mus_musculus 0 2292
ENSMUST00000109629 Gm15557-001 protein_coding Mus_musculus 0 1260

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