C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: neuropilin 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000374867 NRP1-202 ENSG00000099250 9606 - 10:33177494-33334905 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000374867
Transcript ID Adipose Adrenal Bladder Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000374867 36.961±0.00 12.116±0.00 3.563±0.00 12.470±5.01 3.986±2.57 5.650±2.30 4.664±1.93 5.809±1.56 6.317±0.00 1.384±0.44 8.003±6.54 17.346±6.72 2.149±1.37

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006FV CIL_0006FV_0002 CGP 10:32900319-33336262

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001525 IMP:IEA angiogenesis
GO:0001569 ISS patterning of blood vessels
GO:0001764 ISS neuron migration
GO:0001938 TAS positive regulation of endothelial cell proliferation
GO:0002040 ISS sprouting angiogenesis
GO:0002042 ISS cell migration involved in sprouting angiogenesis
GO:0002116 NAS semaphorin receptor complex
GO:0005021 ISS:IEA vascular endothelial growth factor-activated receptor activity
GO:0005515 IPI protein binding
GO:0005615 IDA extracellular space
GO:0005769 ISS early endosome
GO:0005829 IDA cytosol
GO:0005886 IDA plasma membrane
GO:0005925 IDA focal adhesion
GO:0007155 IEA cell adhesion
GO:0007165 TAS signal transduction
GO:0007267 TAS cell-cell signaling
GO:0007411 NAS:IEA axon guidance
GO:0008201 IEA heparin binding
GO:0009887 IEA organ morphogenesis
GO:0010595 TAS positive regulation of endothelial cell migration
GO:0014911 TAS positive regulation of smooth muscle cell migration
GO:0015026 TAS coreceptor activity
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0017154 NAS:IEA semaphorin receptor activity
GO:0019838 TAS growth factor binding
GO:0019955 NAS cytokine binding
GO:0021675 ISS nerve development
GO:0030424 ISS axon
GO:0031290 ISS retinal ganglion cell axon guidance
GO:0031410 TAS cytoplasmic vesicle
GO:0035729 IMP cellular response to hepatocyte growth factor stimulus
GO:0035767 IMP endothelial cell chemotaxis
GO:0035924 ISS cellular response to vascular endothelial growth factor stimulus
GO:0038084 IEA vascular endothelial growth factor signaling pathway
GO:0038085 IPI vascular endothelial growth factor binding
GO:0038190 ISS VEGF-activated neuropilin signaling pathway
GO:0043235 TAS receptor complex
GO:0046872 IEA metal ion binding
GO:0048008 IMP platelet-derived growth factor receptor signaling pathway
GO:0048010 IMP vascular endothelial growth factor receptor signaling pathway
GO:0048012 IMP hepatocyte growth factor receptor signaling pathway
GO:0048842 ISS positive regulation of axon extension involved in axon guidance
GO:0048844 ISS artery morphogenesis
GO:0048846 ISS axon extension involved in axon guidance
GO:0050731 IMP positive regulation of peptidyl-tyrosine phosphorylation
GO:0050918 ISS positive chemotaxis
GO:0060301 TAS positive regulation of cytokine activity
GO:0060385 ISS axonogenesis involved in innervation
GO:0060627 TAS regulation of vesicle-mediated transport
GO:0060978 ISS angiogenesis involved in coronary vascular morphogenesis
GO:0061299 ISS retina vasculature morphogenesis in camera-type eye
GO:0061549 ISS sympathetic ganglion development
GO:0070374 ISS positive regulation of ERK1 and ERK2 cascade
GO:0071526 NAS semaphorin-plexin signaling pathway
GO:0071679 ISS commissural neuron axon guidance
GO:0090259 ISS regulation of retinal ganglion cell axon guidance
GO:0097102 ISS endothelial tip cell fate specification
GO:0097443 ISS sorting endosome
GO:0097490 ISS sympathetic neuron projection extension
GO:0097491 ISS sympathetic neuron projection guidance
GO:1901166 ISS neural crest cell migration involved in autonomic nervous system development
GO:1902285 ISS semaphorin-plexin signaling pathway involved in neuron projection guidance
GO:1902336 ISS positive regulation of retinal ganglion cell axon guidance
GO:1902946 ISS protein localization to early endosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000026917 Nrp1-201 protein_coding Mus_musculus 0 3513

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