C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: caspase 9, apoptosis-related cysteine peptidase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000375890 CASP9-008 ENSG00000132906 9606 - 1:15492855-15524726 protein_coding

Expression Patterns

No expression data.

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004197 IBA:IEA cysteine-type endopeptidase activity
GO:0005515 IPI protein binding
GO:0005829 IDA cytosol
GO:0006508 IEA proteolysis
GO:0006915 TAS:IEA apoptotic process
GO:0006974 IDA cellular response to DNA damage stimulus
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0008047 TAS enzyme activator activity
GO:0008233 IDA peptidase activity
GO:0008234 IEA cysteine-type peptidase activity
GO:0008543 TAS fibroblast growth factor receptor signaling pathway
GO:0008630 IMP intrinsic apoptotic signaling pathway in response to DNA damage
GO:0008635 TAS activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c
GO:0017124 IDA SH3 domain binding
GO:0019901 IDA protein kinase binding
GO:0030220 TAS platelet formation
GO:0034644 IDA cellular response to UV
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0042770 IDA signal transduction in response to DNA damage
GO:0042981 TAS regulation of apoptotic process
GO:0043065 TAS positive regulation of apoptotic process
GO:0043293 IDA apoptosome
GO:0045087 TAS innate immune response
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048015 TAS phosphatidylinositol-mediated signaling
GO:0097193 TAS intrinsic apoptotic signaling pathway
GO:2001020 IMP regulation of response to DNA damage stimulus

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000030747 Casp9-001 protein_coding Mus_musculus 0 817
ENSMUST00000097805 Casp9-003 protein_coding Mus_musculus 0 619
ENSMUST00000138359 Casp9-005 processed_transcript Mus_musculus 8e-35 152
ENSMUST00000128660 Casp9-002 processed_transcript Mus_musculus 8e-35 152
ENSMUST00000153094 Casp9-004 protein_coding Mus_musculus 3e-34 150
ENSDART00000153243 casp7-002 processed_transcript Danio_rerio 0.000007 57
ENSDART00000153406 casp7-001 protein_coding Danio_rerio 0.000007 57

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