C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: methylenetetrahydrofolate reductase (NAD(P)H)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000376583 MTHFR-201 ENSG00000177000 9606 - 1:11785730-11803514 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000376583
Transcript ID Adrenal Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000376583 3.834±0.00 2.411±0.00 2.314±0.00 0.682±0.00 3.316±2.17 2.849±0.00 3.252±2.58 0.966±0.00 5.388±1.81 1.235±0.32 4.396±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00087H CIL_00087H_0001 VISTA 1:11580820-12184055

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004489 IEA:TAS methylenetetrahydrofolate reductase (NAD(P)H) activity
GO:0005829 TAS cytosol
GO:0006520 TAS cellular amino acid metabolic process
GO:0006555 IEA methionine metabolic process
GO:0006766 TAS vitamin metabolic process
GO:0006767 TAS water-soluble vitamin metabolic process
GO:0008015 TAS blood circulation
GO:0035999 IEA tetrahydrofolate interconversion
GO:0044281 TAS small molecule metabolic process
GO:0046655 TAS folic acid metabolic process
GO:0050667 IDA homocysteine metabolic process
GO:0055114 IEA oxidation-reduction process
GO:0072341 IDA modified amino acid binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000069604 Mthfr-001 protein_coding Mus_musculus 0 2305
ENSMUST00000152498 Mthfr-005 nonsense_mediated_decay Mus_musculus 0 2255
ENSMUST00000097788 Mthfr-003 protein_coding Mus_musculus 0 2228
ENSMUST00000141283 Mthfr-002 protein_coding Mus_musculus 0 704
ENSMUST00000174153 Mthfr-ps1-001 processed_pseudogene Mus_musculus 0 608
ENSMUST00000125978 Mthfr-007 retained_intron Mus_musculus 0 566

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