C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: 5,10-methylenetetrahydrofolate reductase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000069604 Mthfr-001 ENSMUSG00000029009 10090 + 4:148041191-148059551 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000069604
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000069604 7.011±1.56 7.177±0.93 6.252±1.00 5.621±3.61 5.250±2.81 2.357±0.78 1.740±0.84 7.566±1.68 3.321±2.10 7.908±0.74 0.759±0.19 7.187±2.54 5.611±2.31 5.776±1.88

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00087H CIL_00087H_0002 VISTA 4:147665245-148272946

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001666 IEA response to hypoxia
GO:0004489 IMP methylenetetrahydrofolate reductase (NAD(P)H) activity
GO:0005829 IEA cytosol
GO:0009086 IMP methionine biosynthetic process
GO:0033274 IEA response to vitamin B2
GO:0035999 IEA tetrahydrofolate interconversion
GO:0042493 IEA response to drug
GO:0043005 IEA neuron projection
GO:0043200 IEA response to amino acid
GO:0046500 IEA S-adenosylmethionine metabolic process
GO:0046653 IEA tetrahydrofolate metabolic process
GO:0050660 IEA flavin adenine dinucleotide binding
GO:0050661 IEA NADP binding
GO:0050667 IEA homocysteine metabolic process
GO:0051593 IEA response to folic acid
GO:0055114 IEA oxidation-reduction process
GO:0070555 IEA response to interleukin-1
GO:0072341 IEA modified amino acid binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000376583 MTHFR-201 protein_coding Homo_sapiens 0 2305
ENST00000376585 MTHFR-007 protein_coding Homo_sapiens 0 2316
ENST00000376590 MTHFR-002 protein_coding Homo_sapiens 0 2228
ENST00000376592 MTHFR-001 protein_coding Homo_sapiens 0 2231
ENST00000418034 MTHFR-004 protein_coding Homo_sapiens 0 531

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