C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: GATA binding protein 1 (globin transcription factor 1)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000376670 GATA1-001 ENSG00000102145 9606 + X:48786554-48794308 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalColonLungOvaryPlacentaTestisENST00000376670
Transcript ID Adipose Adrenal Colon Lung Ovary Placenta Testis
ENST00000376670 0.072±0.00 0.036±0.00 0.341±0.00 3.852±0.00 0.076±0.00 0.321±0.21 0.204±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000976 IMP transcription regulatory region sequence-specific DNA binding
GO:0000977 IDA RNA polymerase II regulatory region sequence-specific DNA binding
GO:0000978 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000981 IEA sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0001077 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001078 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0001085 IPI RNA polymerase II transcription factor binding
GO:0001158 IEA enhancer sequence-specific DNA binding
GO:0001701 IEA in utero embryonic development
GO:0002039 IEA p53 binding
GO:0003677 IDA DNA binding
GO:0003682 IEA chromatin binding
GO:0003700 IDA:IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005667 IDA transcription factor complex
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006366 IDA transcription from RNA polymerase II promoter
GO:0007267 IEA cell-cell signaling
GO:0007596 TAS blood coagulation
GO:0008270 IEA zinc ion binding
GO:0008285 IEA negative regulation of cell proliferation
GO:0008301 IEA DNA binding, bending
GO:0008584 IMP male gonad development
GO:0010559 IMP regulation of glycoprotein biosynthetic process
GO:0010724 IDA regulation of definitive erythrocyte differentiation
GO:0017053 IDA transcriptional repressor complex
GO:0030099 IEA myeloid cell differentiation
GO:0030218 IEP erythrocyte differentiation
GO:0030219 IMP megakaryocyte differentiation
GO:0030220 IMP platelet formation
GO:0030221 IEP basophil differentiation
GO:0030222 IEP eosinophil differentiation
GO:0030502 IEA negative regulation of bone mineralization
GO:0031490 IDA chromatin DNA binding
GO:0033690 IEA positive regulation of osteoblast proliferation
GO:0035162 IEA embryonic hemopoiesis
GO:0035854 IDA eosinophil fate commitment
GO:0043066 IMP negative regulation of apoptotic process
GO:0043565 IMP:IEA sequence-specific DNA binding
GO:0045648 IMP positive regulation of erythrocyte differentiation
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0048468 IEA cell development
GO:0048821 IMP erythrocyte development
GO:0050731 IMP positive regulation of peptidyl-tyrosine phosphorylation
GO:0070527 IMP platelet aggregation
GO:0070742 IPI C2H2 zinc finger domain binding
GO:0071733 ISS transcriptional activation by promoter-enhancer looping
GO:0097028 IEA dendritic cell differentiation
GO:0097067 IDA cellular response to thyroid hormone stimulus
GO:2000678 IDA negative regulation of transcription regulatory region DNA binding
GO:2001240 IMP negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000033502 Gata1-001 protein_coding Mus_musculus 0 1218
ENSMUST00000125418 Gata1-002 protein_coding Mus_musculus 0 348

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