C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: DNA fragmentation factor, 45kDa, alpha polypeptide
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000377038 DFFA-001 ENSG00000160049 9606 - 1:10456522-10472526 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000377038
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000377038 5.114±0.00 3.489±0.00 1.181±0.00 2.679±1.20 3.124±1.26 3.799±2.37 1.586±0.63 2.388±1.14 2.503±0.00 1.491±0.22 1.952±1.07 8.114±3.06 6.233±2.42 5.536±0.11

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008IM CIL_0008IM_0001 VISTA 1:10233066-10834152
CIL_0007WE CIL_0007WE_0001 VISTA 1:10372013-10973061
CIL_00085P CIL_00085P_0001 VISTA 1:10397607-10998574
CIL_00082Y CIL_00082Y_0001 VISTA 1:10421182-11021687
CIL_0008S2 CIL_0008S2_0001 VISTA 1:10435049-11039184
CIL_00019O CIL_00019O_0002 CGP 1:10456522-10630758

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000790 IDA nuclear chromatin
GO:0005515 IPI protein binding
GO:0005622 IEA intracellular
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0005829 IDA cytosol
GO:0006309 TAS apoptotic DNA fragmentation
GO:0006915 TAS:IEA apoptotic process
GO:0006921 TAS cellular component disassembly involved in execution phase of apoptosis
GO:0043065 IEA positive regulation of apoptotic process
GO:0070242 IEA thymocyte apoptotic process
GO:1900118 IDA negative regulation of execution phase of apoptosis
GO:1902511 IDA negative regulation of apoptotic DNA fragmentation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000030816 Dffa-001 protein_coding Mus_musculus 0 832
ENSMUST00000103216 Dffa-002 protein_coding Mus_musculus 0 730
ENSMUST00000153781 Dffa-003 processed_transcript Mus_musculus 1.4013e-45 191
ENSMUST00000162864 Trmt10a-002 protein_coding Mus_musculus 0.000000000007 79
ENSMUST00000040321 Trmt10a-001 protein_coding Mus_musculus 0.000000000007 79
ENSMUST00000024742 Nfkbie-201 protein_coding Mus_musculus 0.000008 58
ENSMUST00000173269 Neu1-002 retained_intron Mus_musculus 0.00003 57
ENSMUST00000121101 Rspry1-002 protein_coding Mus_musculus 0.0001 55

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