C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: tripartite motif containing 27
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000377199 TRIM27-001 ENSG00000204713 9606 - 6:28903002-28923989 protein_coding

Homo sapiens EnsemblGRCh38

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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000377199
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000377199 9.148±0.00 17.069±0.00 0.775±0.00 7.484±3.68 7.018±3.83 4.956±0.84 3.776±2.43 11.786±7.08 9.112±5.85 14.036±0.00 3.309±2.59 16.102±7.11 17.079±2.61 9.694±3.37

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0002820 IMP negative regulation of adaptive immune response
GO:0003676 TAS nucleic acid binding
GO:0003677 IEA DNA binding
GO:0004714 TAS transmembrane receptor protein tyrosine kinase activity
GO:0004842 IDA ubiquitin-protein transferase activity
GO:0005515 IPI:IEA protein binding
GO:0005622 IEA intracellular
GO:0005634 IDA nucleus
GO:0005654 IDA nucleoplasm
GO:0005737 IDA cytoplasm
GO:0005768 IDA endosome
GO:0005887 TAS integral component of plasma membrane
GO:0006351 IEA transcription, DNA-templated
GO:0006469 IDA negative regulation of protein kinase activity
GO:0007283 TAS spermatogenesis
GO:0008270 IEA zinc ion binding
GO:0008283 TAS cell proliferation
GO:0016020 TAS membrane
GO:0016874 IEA ligase activity
GO:0018108 TAS peptidyl-tyrosine phosphorylation
GO:0030904 IDA retromer complex
GO:0031965 IDA nuclear membrane
GO:0032720 IMP negative regulation of tumor necrosis factor production
GO:0032897 IDA negative regulation of viral transcription
GO:0034314 IDA Arp2/3 complex-mediated actin nucleation
GO:0042147 IDA retrograde transport, endosome to Golgi
GO:0045087 IDA innate immune response
GO:0045814 IDA negative regulation of gene expression, epigenetic
GO:0046872 TAS:IEA metal ion binding
GO:0051091 IDA positive regulation of sequence-specific DNA binding transcription factor activity
GO:0070206 IDA protein trimerization
GO:0070534 IMP protein K63-linked ubiquitination
GO:0072643 IMP interferon-gamma secretion
GO:0090281 IMP negative regulation of calcium ion import
GO:1900041 IMP negative regulation of interleukin-2 secretion
GO:1902187 IEA negative regulation of viral release from host cell

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000021761 Trim27-001 protein_coding Mus_musculus 0 2294
ENSMUST00000139287 Trim27-004 nonsense_mediated_decay Mus_musculus 0 654

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