C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: tyrosyl-DNA phosphodiesterase 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000378198 TDP2-001 ENSG00000111802 9606 - 6:24649977-24667033 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000378198
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000378198 10.199±0.00 8.110±0.00 2.974±0.00 9.699±2.50 10.047±3.03 24.318±2.05 5.239±3.33 13.516±10.82 8.021±1.59 6.732±2.11 2.282±1.62 10.317±1.08 6.628±0.78 14.229±8.93

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00036U CIL_00036U_0002 CGP 6:24649977-24705065

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000287 TAS magnesium ion binding
GO:0003697 IDA single-stranded DNA binding
GO:0003714 TAS transcription corepressor activity
GO:0004518 IEA nuclease activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006302 IDA double-strand break repair
GO:0007166 TAS cell surface receptor signaling pathway
GO:0016605 IDA PML body
GO:0030145 IDA manganese ion binding
GO:0036317 IDA tyrosyl-RNA phosphodiesterase activity
GO:0045171 IDA intercellular bridge
GO:0070260 IDA 5'-tyrosyl-DNA phosphodiesterase activity
GO:0090305 IEA nucleic acid phosphodiester bond hydrolysis
GO:2001141 TAS regulation of RNA biosynthetic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000038039 Tdp2-001 protein_coding Mus_musculus 0 756

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