C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: forkhead box O1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000379561 FOXO1-001 ENSG00000150907 9606 - 13:40555667-40666597 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000379561
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000379561 20.722±0.00 8.028±0.00 3.509±0.00 3.886±2.44 10.059±6.02 4.524±3.78 3.532±1.81 4.801±2.28 3.083±2.33 7.395±1.61 26.698±21.74 11.324±6.87 4.740±0.92 5.384±2.65

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00087B CIL_00087B_0001 VISTA 13:40179165-40780133

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0000989 IEA transcription factor binding transcription factor activity
GO:0001078 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0001227 IEA RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0001568 IEA blood vessel development
GO:0001659 ISS temperature homeostasis
GO:0001678 ISS cellular glucose homeostasis
GO:0003677 IEA DNA binding
GO:0003682 ISS chromatin binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0005739 ISS mitochondrion
GO:0005829 ISS cytosol
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006357 IEA regulation of transcription from RNA polymerase II promoter
GO:0006473 ISS protein acetylation
GO:0006914 IEA autophagy
GO:0006915 IEA apoptotic process
GO:0006974 ISS cellular response to DNA damage stimulus
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0008286 ISS insulin receptor signaling pathway
GO:0008543 TAS fibroblast growth factor receptor signaling pathway
GO:0009267 IDA cellular response to starvation
GO:0010508 IMP positive regulation of autophagy
GO:0031018 TAS endocrine pancreas development
GO:0031625 IPI ubiquitin protein ligase binding
GO:0032869 ISS cellular response to insulin stimulus
GO:0032873 IDA negative regulation of stress-activated MAPK cascade
GO:0034599 ISS cellular response to oxidative stress
GO:0035947 IEA regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0042127 IEA regulation of cell proliferation
GO:0042593 IEA glucose homeostasis
GO:0043065 IMP positive regulation of apoptotic process
GO:0043066 IDA negative regulation of apoptotic process
GO:0043565 IDA:IEA sequence-specific DNA binding
GO:0045087 TAS innate immune response
GO:0045444 ISS fat cell differentiation
GO:0045599 ISS negative regulation of fat cell differentiation
GO:0045722 IEA positive regulation of gluconeogenesis
GO:0045732 IMP positive regulation of protein catabolic process
GO:0045892 ISS negative regulation of transcription, DNA-templated
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048015 TAS phosphatidylinositol-mediated signaling
GO:0051721 ISS protein phosphatase 2A binding
GO:0070417 ISS cellular response to cold
GO:0071455 IDA cellular response to hyperoxia
GO:0071732 ISS cellular response to nitric oxide
GO:0090090 IEA negative regulation of canonical Wnt signaling pathway
GO:0097150 IEA neuronal stem cell maintenance
GO:2000177 IEA regulation of neural precursor cell proliferation
GO:2000377 IEA regulation of reactive oxygen species metabolic process
GO:2000505 ISS regulation of energy homeostasis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000053764 Foxo1-001 protein_coding Mus_musculus 0 3544
ENSDART00000124932 FOXO1 (3 of 3)-201 protein_coding Danio_rerio 2e-17 97

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