C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: arachidonate 5-lipoxygenase-activating protein
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000380490 ALOX5AP-001 ENSG00000132965 9606 + 13:30735508-30764426 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000380490
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000380490 19.582±0.00 19.031±0.00 0.351±0.00 8.243±4.61 4.673±3.89 6.479±0.85 4.988±2.66 8.348±7.70 3.673±1.52 47.109±18.02 1.664±0.00 6.689±2.62 28.034±3.74 4.166±2.37

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007UA CIL_0007UA_0001 VISTA 13:30490781-31093754
CIL_0004CN CIL_0004CN_0002 CGP 13:30617693-30764426
CIL_0002AA CIL_0002AA_0001 CGP 13:30713478-30925572

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005635 IDA nuclear envelope
GO:0005783 IDA endoplasmic reticulum
GO:0006691 TAS leukotriene metabolic process
GO:0008047 IEA enzyme activator activity
GO:0016020 IDA membrane
GO:0016021 IEA integral component of membrane
GO:0019369 TAS arachidonic acid metabolic process
GO:0019370 IDA leukotriene biosynthetic process
GO:0019372 TAS lipoxygenase pathway
GO:0031965 IDA nuclear membrane
GO:0043085 IEA positive regulation of catalytic activity
GO:0044281 TAS small molecule metabolic process
GO:0047485 IPI protein N-terminus binding
GO:0050544 IDA arachidonic acid binding
GO:0070207 IPI protein homotrimerization
GO:0071277 IDA cellular response to calcium ion
GO:2001300 TAS lipoxin metabolic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000071130 Alox5ap-201 protein_coding Mus_musculus 0 544
ENSMUST00000130144 Alox5ap-001 protein_coding Mus_musculus 4e-21 106

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