C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: aldo-keto reductase family 1, member C1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000380872 AKR1C1-001 ENSG00000187134 9606 + 10:4963253-4983283 protein_coding

Homo sapiens EnsemblGRCh38

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Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainBreastHeartKidneyLiverOvaryPlacentaTestisENST00000380872
Transcript ID Adrenal Brain Breast Heart Kidney Liver Ovary Placenta Testis
ENST00000380872 0.578±0.00 0.140±0.01 4.026±3.68 0.462±0.00 3.952±0.00 0.844±0.00 0.313±0.00 0.089±0.00 0.768±0.44

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002HN CIL_0002HN_0001 CGP 10:4922564-5135226
CIL_0002HN CIL_0002HN_0002 CGP 10:4963253-5107686

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001523 TAS retinoid metabolic process
GO:0004032 IDA alditol:NADP+ 1-oxidoreductase activity
GO:0004033 TAS aldo-keto reductase (NADP) activity
GO:0005829 IDA cytosol
GO:0006805 NAS xenobiotic metabolic process
GO:0007586 IDA digestion
GO:0007603 TAS phototransduction, visible light
GO:0008206 IDA bile acid metabolic process
GO:0015721 TAS bile acid and bile salt transport
GO:0016655 IDA oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
GO:0018636 IDA phenanthrene 9,10-monooxygenase activity
GO:0030299 TAS intestinal cholesterol absorption
GO:0030855 IDA epithelial cell differentiation
GO:0031406 IDA carboxylic acid binding
GO:0032052 IDA bile acid binding
GO:0042448 IDA progesterone metabolic process
GO:0042574 IDA retinal metabolic process
GO:0042632 TAS cholesterol homeostasis
GO:0044597 IMP daunorubicin metabolic process
GO:0044598 IMP doxorubicin metabolic process
GO:0046683 IEP response to organophosphorus
GO:0047006 IEA 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity
GO:0047042 IDA androsterone dehydrogenase (B-specific) activity
GO:0047086 IDA ketosteroid monooxygenase activity
GO:0047115 IDA trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity
GO:0047718 IEA indanol dehydrogenase activity
GO:0051260 IDA protein homooligomerization
GO:0055114 IDA oxidation-reduction process
GO:0070062 IDA extracellular vesicular exosome
GO:0071395 IDA cellular response to jasmonic acid stimulus

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000021635 Akr1c18-001 protein_coding Mus_musculus 0 726
ENSMUST00000080361 Akr1c20-002 protein_coding Mus_musculus 0 658
ENSMUST00000078239 Akr1c20-001 protein_coding Mus_musculus 0 431
ENSMUST00000110704 Akr1c18-002 protein_coding Mus_musculus 0 420

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