C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: nuclear receptor subfamily 1, group H, member 4
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000392986 NR1H4-003 ENSG00000012504 9606 + 12:100473916-100563503 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; KidneyLiverOvaryENST00000392986
Transcript ID Kidney Liver Ovary
ENST00000392986 4.017±0.00 3.970±0.00 1.509±0.48

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006BW CIL_0006BW_0002 CGP 12:100357079-100564413

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 ISS negative regulation of transcription from RNA polymerase II promoter
GO:0000980 IDA RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0001080 IC nitrogen catabolite activation of transcription from RNA polymerase II promoter
GO:0001190 IDA RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription
GO:0003700 TAS:IEA sequence-specific DNA binding transcription factor activity
GO:0003705 IDA RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0003707 IEA steroid hormone receptor activity
GO:0003713 TAS transcription coactivator activity
GO:0003714 TAS transcription corepressor activity
GO:0004879 ISS ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0004887 IEA thyroid hormone receptor activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0005719 IDA nuclear euchromatin
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006367 TAS transcription initiation from RNA polymerase II promoter
GO:0007165 TAS signal transduction
GO:0008270 IEA zinc ion binding
GO:0010467 TAS gene expression
GO:0016922 TAS ligand-dependent nuclear receptor binding
GO:0030522 ISS intracellular receptor signaling pathway
GO:0032052 ISS bile acid binding
GO:0034255 ISS regulation of urea metabolic process
GO:0038181 IDA bile acid receptor activity
GO:0038185 IDA intracellular bile acid receptor signaling pathway
GO:0043401 IEA steroid hormone mediated signaling pathway
GO:0043565 IDA:IEA sequence-specific DNA binding
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0070857 TAS regulation of bile acid biosynthetic process
GO:0070858 IDA negative regulation of bile acid biosynthetic process
GO:0071417 ISS cellular response to organonitrogen compound
GO:0090181 TAS regulation of cholesterol metabolic process
GO:1902122 IDA chenodeoxycholic acid binding
GO:1903413 ISS cellular response to bile acid
GO:2000213 ISS positive regulation of glutamate metabolic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000142170 thrb-002 processed_transcript Danio_rerio 0.00000000000004 84
ENSDART00000017869 thrb-001 nonsense_mediated_decay Danio_rerio 0.00000000000004 84
ENSDART00000151766 thrb-003 protein_coding Danio_rerio 0.00000000000004 84

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