C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000394464 NR3C1-002 ENSG00000113580 9606 - 5:143277931-143403700 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENST00000394464
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENST00000394464 2.911±0.00 1.692±0.00 2.373±0.00 2.098±0.00 5.129±1.11 2.757±0.29 1.844±0.34 4.335±0.00 5.401±4.16 5.423±2.14 6.182±1.69 1.120±0.37 2.716±0.34

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677 IEA DNA binding
GO:0003700 TAS:IEA sequence-specific DNA binding transcription factor activity
GO:0003707 IEA steroid hormone receptor activity
GO:0004883 IEA glucocorticoid receptor activity
GO:0005496 IEA steroid binding
GO:0005515 IPI protein binding
GO:0005634 IDA:IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0005759 TAS mitochondrial matrix
GO:0006351 TAS transcription, DNA-templated
GO:0006355 IDA:IEA regulation of transcription, DNA-templated
GO:0006366 TAS transcription from RNA polymerase II promoter
GO:0006367 TAS transcription initiation from RNA polymerase II promoter
GO:0007165 TAS signal transduction
GO:0008270 IEA zinc ion binding
GO:0010467 TAS gene expression
GO:0016568 IEA chromatin modification
GO:0042921 IEA glucocorticoid receptor signaling pathway
GO:0043401 IEA steroid hormone mediated signaling pathway
GO:0043402 IEA glucocorticoid mediated signaling pathway
GO:0043565 IEA sequence-specific DNA binding
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000115571 Nr3c1-201 protein_coding Mus_musculus 0 4549
ENSMUST00000025300 Nr3c1-002 protein_coding Mus_musculus 0 4549
ENSMUST00000115567 Nr3c1-001 protein_coding Mus_musculus 0 4549
ENSMUST00000097592 Nr3c1-004 protein_coding Mus_musculus 0 2695
ENSMUST00000152853 Nr3c1-003 protein_coding Mus_musculus 0 1443

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