C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: aurora kinase A
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000395911 AURKA-010 ENSG00000087586 9606 - 20:56369390-56392215 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; ColonKidneyLiverOvaryENST00000395911
Transcript ID Colon Kidney Liver Ovary
ENST00000395911 0.676±0.00 1.697±0.00 0.327±0.00 0.262±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00099D CIL_00099D_0001 VISTA 20:56155251-56756351
CIL_0001I0 CIL_0001I0_0001 CGP 20:56358915-56392337
CIL_0002PV CIL_0002PV_0001 CGP 20:56369389-56406369

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000086 TAS G2/M transition of mitotic cell cycle
GO:0000278 TAS mitotic cell cycle
GO:0004672 IDA:IEA protein kinase activity
GO:0004674 EXP protein serine/threonine kinase activity
GO:0004712 TAS protein serine/threonine/tyrosine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005813 IDA centrosome
GO:0005819 TAS spindle
GO:0005829 TAS cytosol
GO:0005876 IDA spindle microtubule
GO:0006468 IDA:IEA protein phosphorylation
GO:0007067 TAS mitotic nuclear division
GO:0015630 IDA microtubule cytoskeleton
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0019901 IPI protein kinase binding
GO:0030496 TAS midbody
GO:0031145 TAS anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0031616 IDA spindle pole centrosome
GO:0031647 IMP regulation of protein stability
GO:0032091 IDA negative regulation of protein binding
GO:0043146 IMP spindle stabilization
GO:0045840 TAS positive regulation of mitosis
GO:0046605 TAS regulation of centrosome cycle
GO:0046777 TAS protein autophosphorylation
GO:0048471 IDA perinuclear region of cytoplasm

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000028997 Aurka-201 protein_coding Mus_musculus 0 793
ENSMUST00000109139 Aurka-002 protein_coding Mus_musculus 0 793
ENSMUST00000109140 Aurka-001 protein_coding Mus_musculus 0 793

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