C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: myeloid differentiation primary response 88
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000396334 MYD88-001 ENSG00000172936 9606 + 3:38138478-38143022 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000396334
Transcript ID Adipose Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000396334 3.370±0.00 3.707±0.76 0.923±0.00 1.666±0.00 3.145±0.00 8.917±0.00 7.807±0.00 10.103±4.78 12.980±6.53 2.033±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002224 TAS toll-like receptor signaling pathway
GO:0002755 TAS:IEA MyD88-dependent toll-like receptor signaling pathway
GO:0005123 TAS death receptor binding
GO:0005515 IPI:IEA protein binding
GO:0005829 TAS cytosol
GO:0005886 TAS plasma membrane
GO:0006954 IEA inflammatory response
GO:0007165 NAS:IEA signal transduction
GO:0007166 TAS cell surface receptor signaling pathway
GO:0010008 TAS endosome membrane
GO:0032481 TAS positive regulation of type I interferon production
GO:0032740 ISS positive regulation of interleukin-17 production
GO:0032747 ISS positive regulation of interleukin-23 production
GO:0032755 ISS positive regulation of interleukin-6 production
GO:0034134 TAS toll-like receptor 2 signaling pathway
GO:0034142 TAS toll-like receptor 4 signaling pathway
GO:0034146 TAS toll-like receptor 5 signaling pathway
GO:0034162 TAS toll-like receptor 9 signaling pathway
GO:0034166 TAS toll-like receptor 10 signaling pathway
GO:0038123 TAS toll-like receptor TLR1:TLR2 signaling pathway
GO:0038124 TAS toll-like receptor TLR6:TLR2 signaling pathway
GO:0042802 IPI identical protein binding
GO:0043066 TAS negative regulation of apoptotic process
GO:0043123 IEP:IEA positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045087 TAS innate immune response
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0050727 ISS regulation of inflammatory response
GO:0050830 ISS defense response to Gram-positive bacterium
GO:0070555 IMP response to interleukin-1
GO:0070935 IDA 3'-UTR-mediated mRNA stabilization
GO:0070976 IPI:IEA TIR domain binding
GO:0071260 IEP cellular response to mechanical stimulus

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000035092 Myd88-001 protein_coding Mus_musculus 0 767
ENSMUST00000150837 Myd88-002 retained_intron Mus_musculus 0 311

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