C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: Rap guanine nucleotide exchange factor (GEF) 5
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000401957 RAPGEF5-001 ENSG00000136237 9606 - 7:22118238-22193909 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainBreastColonHeartLiverMuscleOvaryENST00000401957
Transcript ID Brain Breast Colon Heart Liver Muscle Ovary
ENST00000401957 11.930±6.47 1.999±0.00 2.133±0.00 0.456±0.00 0.534±0.00 0.438±0.00 0.758±0.41

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008OS CIL_0008OS_0001 VISTA 7:21751744-22352939

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005085 IEA guanyl-nucleotide exchange factor activity
GO:0005088 TAS Ras guanyl-nucleotide exchange factor activity
GO:0005622 IEA intracellular
GO:0005634 IDA nucleus
GO:0007264 NAS:IEA small GTPase mediated signal transduction
GO:0007399 NAS nervous system development
GO:0017034 IDA Rap guanyl-nucleotide exchange factor activity
GO:0030742 IPI GTP-dependent protein binding
GO:0032320 TAS positive regulation of Ras GTPase activity
GO:0032854 IDA positive regulation of Rap GTPase activity
GO:0043547 IEA positive regulation of GTPase activity
GO:0051056 IEA regulation of small GTPase mediated signal transduction

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000109691 Rapgef5-201 protein_coding Mus_musculus 0 2025

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