C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: pyrroline-5-carboxylate reductase 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000402252 PYCR1-003 ENSG00000183010 9606 - 17:81932935-81937239 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainBreastColonKidneyLiverOvaryPlacentaTestisENST00000402252
Transcript ID Adrenal Brain Breast Colon Kidney Liver Ovary Placenta Testis
ENST00000402252 2.893±0.00 1.463±0.00 1.372±0.00 2.098±0.00 2.227±0.00 0.926±0.00 11.405±2.82 5.774±1.80 2.813±1.09

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006IG CIL_0006IG_0001 CGP 17:81918270-81942412
CIL_0004VN CIL_0004VN_0001 CGP 17:81932384-81947233

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004735 IEA:IDA pyrroline-5-carboxylate reductase activity
GO:0005515 IPI protein binding
GO:0005737 IEA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005759 TAS mitochondrial matrix
GO:0006561 IEA:IDA proline biosynthetic process
GO:0008652 TAS cellular amino acid biosynthetic process
GO:0016616 IEA oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0034599 IMP cellular response to oxidative stress
GO:0034641 TAS cellular nitrogen compound metabolic process
GO:0042802 IPI identical protein binding
GO:0044281 TAS small molecule metabolic process
GO:0046168 IEA glycerol-3-phosphate catabolic process
GO:0051287 IEA NAD binding
GO:0051881 IMP regulation of mitochondrial membrane potential
GO:0055114 IEA oxidation-reduction process
GO:0055129 IEA L-proline biosynthetic process
GO:1903206 IMP negative regulation of hydrogen peroxide-induced cell death

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000026133 Pycr1-001 protein_coding Mus_musculus 0 1031
ENSMUST00000170556 Pycr1-201 protein_coding Mus_musculus 0 1018
ENSMUST00000141254 Pycr1-003 protein_coding Mus_musculus 0 802
ENSMUST00000151876 Pycr1-005 protein_coding Mus_musculus 0 562
ENSMUST00000139706 Pycr1-002 protein_coding Mus_musculus 0 510
ENSDART00000130298 pycr1a-201 protein_coding Danio_rerio 0 496
ENSDART00000076080 pycr1a-001 protein_coding Danio_rerio 0 496

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