C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: proteasome (prosome, macropain) activator subunit 4
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000404125 PSME4-001 ENSG00000068878 9606 - 2:53864067-53970840 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000404125
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000404125 2.579±0.00 2.371±0.00 2.170±1.56 3.430±0.76 3.076±0.00 7.765±5.69 3.679±0.12 3.296±1.49 3.723±0.00 8.732±5.13 4.387±1.20 2.051±0.34 11.275±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000209 TAS protein polyubiquitination
GO:0000278 TAS mitotic cell cycle
GO:0002474 TAS antigen processing and presentation of peptide antigen via MHC class I
GO:0002479 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0005488 IEA binding
GO:0005634 ISS nucleus
GO:0005829 ISS cytosol
GO:0006281 ISS DNA repair
GO:0006521 TAS regulation of cellular amino acid metabolic process
GO:0006915 TAS apoptotic process
GO:0006974 ISS cellular response to DNA damage stimulus
GO:0006977 TAS DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0007275 IEA multicellular organismal development
GO:0010467 TAS gene expression
GO:0010499 ISS proteasomal ubiquitin-independent protein catabolic process
GO:0010952 IEA positive regulation of peptidase activity
GO:0016032 TAS viral process
GO:0016070 TAS RNA metabolic process
GO:0016071 TAS mRNA metabolic process
GO:0016504 ISS peptidase activator activity
GO:0031145 TAS anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0034641 TAS cellular nitrogen compound metabolic process
GO:0035093 ISS spermatogenesis, exchange of chromosomal proteins
GO:0042590 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0042981 TAS regulation of apoptotic process
GO:0043066 TAS negative regulation of apoptotic process
GO:0044281 TAS small molecule metabolic process
GO:0051437 TAS positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051439 TAS regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0070577 ISS lysine-acetylated histone binding
GO:1990111 ISS spermatoproteasome complex

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000041231 Psme4-001 protein_coding Mus_musculus 0 7926
ENSMUST00000154757 Psme4-002 protein_coding Mus_musculus 0 569
ENSMUST00000129824 Psme4-006 protein_coding Mus_musculus 0 399
ENSMUST00000142217 Psme4-004 processed_transcript Mus_musculus 0 383
ENSMUST00000133430 Psme4-003 processed_transcript Mus_musculus 0 370
ENSMUST00000150219 Psme4-005 processed_transcript Mus_musculus 0 213
ENSMUST00000155719 Psme4-007 processed_transcript Mus_musculus 3e-40 172

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