C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: clusterin
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000405140 CLU-004 ENSG00000120885 9606 - 8:27597808-27611431 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000405140
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000405140 52.845±0.00 165.455±0.00 6.847±0.00 458.188±360.21 224.794±0.00 202.612±0.00 12.963±0.00 165.310±27.79 193.393±177.81 33.025±25.38 185.001±222.39 24.878±3.33 485.087±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0009DK CIL_0009DK_0001 VISTA 8:27594923-28195834
CIL_0005SQ CIL_0005SQ_0002 CGP 8:27596917-27676776

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000902 IDA cell morphogenesis
GO:0001774 IDA microglial cell activation
GO:0001836 IC release of cytochrome c from mitochondria
GO:0002576 TAS platelet degranulation
GO:0005515 IPI protein binding
GO:0005576 TAS extracellular region
GO:0005615 IDA extracellular space
GO:0005634 IEA nucleus
GO:0005737 IDA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005783 IEA endoplasmic reticulum
GO:0006629 NAS lipid metabolic process
GO:0006956 TAS complement activation
GO:0006958 IEA complement activation, classical pathway
GO:0007596 TAS blood coagulation
GO:0008219 IEA cell death
GO:0009615 IEP response to virus
GO:0016020 IEA membrane
GO:0017038 IDA protein import
GO:0030168 TAS platelet activation
GO:0031012 IDA extracellular matrix
GO:0031093 TAS platelet alpha granule lumen
GO:0031625 IDA ubiquitin protein ligase binding
GO:0032286 IMP central nervous system myelin maintenance
GO:0032436 IMP positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0032463 IMP negative regulation of protein homooligomerization
GO:0032760 IDA positive regulation of tumor necrosis factor production
GO:0034366 IDA spherical high-density lipoprotein particle
GO:0043065 IMP positive regulation of apoptotic process
GO:0043691 TAS reverse cholesterol transport
GO:0045087 IEA innate immune response
GO:0045429 IDA positive regulation of nitric oxide biosynthetic process
GO:0048471 IDA perinuclear region of cytoplasm
GO:0050821 IDA protein stabilization
GO:0051092 IMP positive regulation of NF-kappaB transcription factor activity
GO:0051131 IDA chaperone-mediated protein complex assembly
GO:0051787 IDA misfolded protein binding
GO:0051788 IDA response to misfolded protein
GO:0061077 IDA chaperone-mediated protein folding
GO:0061518 IDA microglial cell proliferation
GO:0070062 IDA extracellular vesicular exosome
GO:0072562 IDA blood microparticle
GO:0097193 IDA intrinsic apoptotic signaling pathway
GO:0097418 IDA neurofibrillary tangle
GO:0097440 IDA apical dendrite
GO:1900221 IDA regulation of beta-amyloid clearance
GO:1901214 IDA regulation of neuron death
GO:1901216 IDA positive regulation of neuron death
GO:1902004 ISS positive regulation of beta-amyloid formation
GO:1902230 IMP negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:1902430 IDA negative regulation of beta-amyloid formation
GO:1902847 IMP regulation of neuronal signal transduction
GO:1902949 IMP positive regulation of tau-protein kinase activity
GO:1902998 IMP positive regulation of neurofibrillary tangle assembly
GO:2000060 IMP positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:2001244 IMP positive regulation of intrinsic apoptotic signaling pathway

Homologs

No Homologs available.

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