C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: B-cell CLL/lymphoma 6
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000406870 BCL6-001 ENSG00000113916 9606 - 3:187721377-187745727 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainColonLiverOvaryTestisENST00000406870
Transcript ID Adrenal Bladder Brain Colon Liver Ovary Testis
ENST00000406870 2.270±0.00 0.897±0.00 2.048±1.39 5.238±0.00 2.376±0.00 3.229±2.59 4.433±2.94

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00003X CIL_00003X_0001 CGP 3:187698259-187745727
CIL_0003Y6 CIL_0003Y6_0002 CGP 3:187721377-188890671

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000060 IGI protein import into nucleus, translocation
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000902 IEA cell morphogenesis
GO:0000977 IEA RNA polymerase II regulatory region sequence-specific DNA binding
GO:0001227 IEA RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0001953 IEA negative regulation of cell-matrix adhesion
GO:0002467 IEA germinal center formation
GO:0002634 NAS regulation of germinal center formation
GO:0002829 IEA negative regulation of type 2 immune response
GO:0002903 NAS negative regulation of B cell apoptotic process
GO:0003677 IEA DNA binding
GO:0003682 IDA chromatin binding
GO:0003700 IMP sequence-specific DNA binding transcription factor activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005657 IDA replication fork
GO:0006351 IEA transcription, DNA-templated
GO:0006954 IEA inflammatory response
GO:0006974 IDA cellular response to DNA damage stimulus
GO:0007266 IEA Rho protein signal transduction
GO:0007283 IEA spermatogenesis
GO:0008104 IEA protein localization
GO:0008285 IEA negative regulation of cell proliferation
GO:0030036 IEA actin cytoskeleton organization
GO:0030183 IEA B cell differentiation
GO:0030308 IDA negative regulation of cell growth
GO:0030890 IEA positive regulation of B cell proliferation
GO:0031065 IEA positive regulation of histone deacetylation
GO:0031490 IEA chromatin DNA binding
GO:0032319 IEA regulation of Rho GTPase activity
GO:0032764 IEA negative regulation of mast cell cytokine production
GO:0035024 IEA negative regulation of Rho protein signal transduction
GO:0042092 IEA type 2 immune response
GO:0042127 IEA regulation of cell proliferation
GO:0043065 IDA positive regulation of apoptotic process
GO:0043066 IEA negative regulation of apoptotic process
GO:0043380 IEA regulation of memory T cell differentiation
GO:0043565 IDA sequence-specific DNA binding
GO:0045596 IEA negative regulation of cell differentiation
GO:0045629 IEA negative regulation of T-helper 2 cell differentiation
GO:0045666 IEA positive regulation of neuron differentiation
GO:0045746 IEA negative regulation of Notch signaling pathway
GO:0045892 IMP negative regulation of transcription, DNA-templated
GO:0046872 IEA metal ion binding
GO:0048294 IEA negative regulation of isotype switching to IgE isotypes
GO:0048821 IEA erythrocyte development
GO:0050727 IEA regulation of inflammatory response
GO:0050776 NAS regulation of immune response
GO:0051272 IEA positive regulation of cellular component movement
GO:2000773 IEA negative regulation of cellular senescence

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000023151 Bcl6-001 protein_coding Mus_musculus 0 4298
ENSMUST00000135352 Bcl6-002 retained_intron Mus_musculus 0 377
ENSDART00000131126 bcl6a-001 protein_coding Danio_rerio 1e-31 143

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